Dermal nevus - Revision history

Mikael Häggström: Not there

2022-12-02T20:32:58Z

Not there

← Older revision		Revision as of 16:32, 2 December 2022
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	===Grading===		===Grading===
	{{Moderate-begin}}Grade a dermal nevus into either low or high grade by the following algorithm:{{Moderate-end}}<ref>{{cite journal\|last1=Pozo\|first1=Lucia\|last2=Naase\|first2=Mahmoud\|last3=Cerio\|first3=Rino\|last4=Blanes\|first4=Alfredo\|last5=Diaz-Cano\|first5=Salvador J.\|title=Critical Analysis of Histologic Criteria for Grading Atypical (Dysplastic) Melanocytic Nevi\|journal=American Journal of Clinical Pathology\|volume=115\|issue=2\|year=2001\|pages=194–204\|issn=0002-9173\|doi=10.1309/KXJW-1UJE-BPG6-AXBV}}</ref~~><ref group="notes" name="regression"/~~>		{{Moderate-begin}}Grade a dermal nevus into either low or high grade by the following algorithm:{{Moderate-end}}<ref>{{cite journal\|last1=Pozo\|first1=Lucia\|last2=Naase\|first2=Mahmoud\|last3=Cerio\|first3=Rino\|last4=Blanes\|first4=Alfredo\|last5=Diaz-Cano\|first5=Salvador J.\|title=Critical Analysis of Histologic Criteria for Grading Atypical (Dysplastic) Melanocytic Nevi\|journal=American Journal of Clinical Pathology\|volume=115\|issue=2\|year=2001\|pages=194–204\|issn=0002-9173\|doi=10.1309/KXJW-1UJE-BPG6-AXBV}}</ref>
	[[File:Algorithm for low grade versus high grade dysplastic nevus.png\|center\|250px]]		[[File:Algorithm for low grade versus high grade dysplastic nevus.png\|center\|250px]]

Mikael Häggström: /* Microscopic evaluation */ +Images

2021-05-15T18:29:23Z

Microscopic evaluation: +Images

← Older revision		Revision as of 14:29, 15 May 2021
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	*Irregularly distributed dermal nests of melanocytes.<ref name=KVAST/>		*Irregularly distributed dermal nests of melanocytes.<ref name=KVAST/>
	*Atypia		*Atypia
			<gallery mode=packed heights=190>
			File:Histopathology of dermal nevus, high magnification.jpg\|'''Dermal nevus'''
			File:Histopathology of intradermal nevus with multinucleated melanocytes, medium magnification.jpg\|A '''dermal nevus''' infrequently shows multinucleated '''giant cells''' as shown.<ref>{{cite web\|url=https://www.pathologyoutlines.com/topic/skintumormelanocyticdermalnevus.html\|title=Skin melanocytic tumor - Dermal nevus\|author=Christopher S. Hale, M.D.\|website=PathologyOutlines}} Topic Completed: 1 August 2014. Minor changes: 21 September 2020</ref>
			</gallery>

	===Subtyping===		===Subtyping===

Mikael Häggström: dupe

2021-04-09T12:14:09Z

dupe

← Older revision		Revision as of 08:14, 9 April 2021
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	\|author2=		\|author2=
	}}		}}
	A suspected dermal (or '''intra'''dermal ~~nevus~~ nevus) generally presents as a [[Dark skin focalities\|dark skin focality]].		A suspected dermal (or '''intra'''dermal nevus) generally presents as a [[Dark skin focalities\|dark skin focality]].
	{{Gross processing of skin excisions}}		{{Gross processing of skin excisions}}
	{{Comprehensiveness}}		{{Comprehensiveness}}

Mikael Häggström: /* Report */ Low grade

2020-12-01T20:38:19Z

Report: Low grade

← Older revision		Revision as of 16:38, 1 December 2020
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	Example:		Example:
	{\|class=wikitable		{\|class=wikitable
	\| {{Moderate-begin}}Skin, right upper chest, shave biopsy:{{Moderate-end}}<br>Intradermal nevus.		\| {{Moderate-begin}}Skin, right upper chest, shave biopsy:{{Moderate-end}}<br>Intradermal {{Moderate-begin}}low-grade{{Moderate-end}} nevus.
	\|}		\|}

	{{Reporting}}		{{Reporting}}
	{{Bottom}}		{{Bottom}}

Mikael Häggström: /* Report */ Example

2020-12-01T20:37:20Z

Report: Example

← Older revision		Revision as of 16:37, 1 December 2020
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	*Diagnosis of dermal nevus.		*Diagnosis of dermal nevus.
	*{{Moderate-begin}}Most likely grade.{{Moderate-end}}		*{{Moderate-begin}}Most likely grade.{{Moderate-end}}
			Example:
			{\|class=wikitable
			\| {{Moderate-begin}}Skin, right upper chest, shave biopsy:{{Moderate-end}}<br>Intradermal nevus.
			\|}

	{{Reporting}}		{{Reporting}}
	{{Bottom}}		{{Bottom}}

Mikael Häggström: Edit

2020-12-01T20:35:40Z

Edit

← Older revision		Revision as of 16:35, 1 December 2020
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	A suspected dermal (or '''intra'''dermal nevus nevus) generally presents as a [[Dark skin focalities\|dark skin focality]].		A suspected dermal (or '''intra'''dermal nevus nevus) generally presents as a [[Dark skin focalities\|dark skin focality]].
	{{Gross processing of skin excisions}}		{{Gross processing of skin excisions}}
			{{Comprehensiveness}}
	==Microscopic evaluation==		==Microscopic evaluation==
	*Irregularly distributed dermal nests of melanocytes.<ref name=KVAST/>		*Irregularly distributed dermal nests of melanocytes.<ref name=KVAST/>
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	===Grading===		===Grading===
	~~It is acceptable to grade~~ a dermal nevus into either low or high grade by the following algorithm:<ref>{{cite journal\|last1=Pozo\|first1=Lucia\|last2=Naase\|first2=Mahmoud\|last3=Cerio\|first3=Rino\|last4=Blanes\|first4=Alfredo\|last5=Diaz-Cano\|first5=Salvador J.\|title=Critical Analysis of Histologic Criteria for Grading Atypical (Dysplastic) Melanocytic Nevi\|journal=American Journal of Clinical Pathology\|volume=115\|issue=2\|year=2001\|pages=194–204\|issn=0002-9173\|doi=10.1309/KXJW-1UJE-BPG6-AXBV}}</ref><ref group="notes" name="regression"/>		{{Moderate-begin}}Grade a dermal nevus into either low or high grade by the following algorithm:{{Moderate-end}}<ref>{{cite journal\|last1=Pozo\|first1=Lucia\|last2=Naase\|first2=Mahmoud\|last3=Cerio\|first3=Rino\|last4=Blanes\|first4=Alfredo\|last5=Diaz-Cano\|first5=Salvador J.\|title=Critical Analysis of Histologic Criteria for Grading Atypical (Dysplastic) Melanocytic Nevi\|journal=American Journal of Clinical Pathology\|volume=115\|issue=2\|year=2001\|pages=194–204\|issn=0002-9173\|doi=10.1309/KXJW-1UJE-BPG6-AXBV}}</ref><ref group="notes" name="regression"/>
	[[File:Algorithm for low grade versus high grade dysplastic nevus.png\|center\|250px]]		[[File:Algorithm for low grade versus high grade dysplastic nevus.png\|center\|250px]]

	In uncertain cases, more specific grading, and/or differentiation from a non-atypical congenital nevus and suspected [[invasive melanoma of the skin\|invasive melanoma]], the following table can be used to determine the most fitting diagnosis:		In uncertain cases,{{Comprehensive-begin}} more specific grading,{{Comprehensive-end}} and/or differentiation from a non-atypical congenital nevus and suspected [[invasive melanoma of the skin\|invasive melanoma]], the following table can be used to determine the most fitting diagnosis:

	{{Table comparing dermal nevus and suspected invasive melanoma}}		{{Table comparing dermal nevus and suspected invasive melanoma}}
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	===Report===		===Report===
	*~~Size~~		*Diagnosis of dermal nevus.
	*Preferably findings included in table.		*{{Moderate-begin}}Most likely grade.{{Moderate-end}}
	*Most likely grade ~~if possible~~.
	{{Reporting}}		{{Reporting}}
	{{Bottom}}		{{Bottom}}

Mikael Häggström: Also called intra

2020-12-01T20:30:19Z

Also called intra

← Older revision		Revision as of 16:30, 1 December 2020
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	\|author2=		\|author2=
	}}		}}
	A suspected dermal nevus generally presents as a [[Dark skin focalities\|dark skin focality]].		A suspected dermal (or '''intra'''dermal nevus nevus) generally presents as a [[Dark skin focalities\|dark skin focality]].
	{{Gross processing of skin excisions}}		{{Gross processing of skin excisions}}
	==Microscopic evaluation==		==Microscopic evaluation==

Mikael Häggström: /* Grading */ +Not always

2020-10-05T12:58:08Z

Grading: +Not always

← Older revision		Revision as of 08:58, 5 October 2020
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	{{Table comparing dermal nevus and suspected invasive melanoma}}		{{Table comparing dermal nevus and suspected invasive melanoma}}
			[[File:Histopathology of dermal nevus on the ear with traumatic epidermal atypia.jpg\|thumb\|center\|220px\|'''Non-dysplastic''' dermal nevus on the ear with minor epidermal atypia, which on this location does not indicate dysplasia.]]

	===Report===		===Report===

Mikael Häggström: /* Differential diagnosis */ +Compound

2020-10-05T12:56:07Z

Differential diagnosis: +Compound

← Older revision		Revision as of 08:56, 5 October 2020
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	<gallery mode=packed heights=200>		<gallery mode=packed heights=200>
	File:Histopathology of melanocytic nevus 2.jpg\|'''[[Junctional nevus]]''' (here seen in H&E stain and Melan A stain), where all nests are continuous with the epidermis.		File:Histopathology of melanocytic nevus 2.jpg\|'''[[Junctional nevus]]''' (here seen in H&E stain and Melan A stain), where all nests are continuous with the epidermis.
	File:Histopathology of ~~dermal~~ nevus ~~on the ear with traumatic epidermal atypia~~.jpg\|~~However~~, ~~this is a non-dysplastic dermal~~ nevus ~~on the ear with minor epidermal atypia, which on this location does not indicate dysplasia~~.		File:Histopathology of compound nevus.jpg\|thumb\|'''Compound nevus''', with nevus cells in both dermis and epidermis.
	File:Histopathology of invasive acral lentiginous melanoma.jpg\|'''[[Invasive melanoma of the skin]]''', has more atypia and dysplasia (see table in [[#Grading\|the grading section]]).		File:Histopathology of invasive acral lentiginous melanoma.jpg\|'''[[Invasive melanoma of the skin]]''', has more atypia and dysplasia (see table in [[#Grading\|the grading section]]).
	</gallery>		</gallery>

Mikael Häggström: /* Microscopic evaluation */ +Subtyping

2020-09-01T20:19:16Z

Microscopic evaluation: +Subtyping

← Older revision		Revision as of 16:19, 1 September 2020
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	*Irregularly distributed dermal nests of melanocytes.<ref name=KVAST/>		*Irregularly distributed dermal nests of melanocytes.<ref name=KVAST/>
	*Atypia		*Atypia

			===Subtyping===
			[[File:Blue nevus (4 of 4) (2797064219).jpg\|thumb\|center\|link=Blue nevus\|'''Blue nevus''': Where the pigment is deeper in the skin than in ordinary nevi.]]

	===Differential diagnosis===		===Differential diagnosis===