Duodenum - Revision history

Mikael Häggström: /* Others */ + Active

2023-11-27T15:41:44Z

Others: + Active

← Older revision		Revision as of 11:41, 27 November 2023
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	File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>,<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref> and is best evaluated at tips of villi<ref name="pmid15280404">{{cite journal\| author=Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V \| display-authors=etal\| title=Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? \| journal=J Clin Pathol \| year= 2004 \| volume= 57 \| issue= 8 \| pages= 835-9 \| pmid=15280404 \| doi=10.1136/jcp.2003.013607 \| pmc=1770380 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15280404 }} </ref>.<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>		File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>,<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref> and is best evaluated at tips of villi<ref name="pmid15280404">{{cite journal\| author=Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V \| display-authors=etal\| title=Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? \| journal=J Clin Pathol \| year= 2004 \| volume= 57 \| issue= 8 \| pages= 835-9 \| pmid=15280404 \| doi=10.1136/jcp.2003.013607 \| pmc=1770380 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15280404 }} </ref>.<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>
	File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''		File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''
			File:Duodenal biopsy with chronic active peptic duodenitis.jpg\|The addition of a neutrophilic infiltrate in case of peptic injury confers a diagnosis of '''chronic active duodenitis'''
	File:Histopathology of Giardia lamblia in duodenum.png\|Also take a quick look in crypts for any '''Giardia''' organisms.		File:Histopathology of Giardia lamblia in duodenum.png\|Also take a quick look in crypts for any '''Giardia''' organisms.
	</gallery>		</gallery>

Mikael Häggström: /* Report */ list

2023-11-24T15:47:40Z

Report: list

← Older revision		Revision as of 11:47, 24 November 2023
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	Example in a normal case:		Example in a normal case:
	{\|class=wikitable		{\|class=wikitable
	\| (Duodenum, biopsy:) Duodenal mucosa without significant histopathologic changes. (Negative for celiac disease.)		\| (Duodenum, biopsy:)
			*Duodenal mucosa without significant histopathologic changes.
			*(Negative for celiac disease.)
	\|}		\|}

	Example in (chronic) peptic injury:		Example in (chronic) peptic injury:
	{\|class=wikitable		{\|class=wikitable
	\| (Small bowel, biopsy:) Small intestinal mucosa with histologic changes consistent with chronic peptic injury. (Negative for celiac disease.)		\| (Small bowel, biopsy:)
			*Small intestinal mucosa with histologic changes consistent with chronic peptic injury.
			*(Negative for celiac disease.)
	\|}		\|}
	{{Bottom}}		{{Bottom}}

Mikael Häggström: Injury

2022-12-16T23:36:27Z

Injury

← Older revision		Revision as of 19:36, 16 December 2022
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	*Giardia organisms		*Giardia organisms

	===Peptic ~~duodenitis~~===		===Peptic injury===
	Peptic duodenitis typically showing the following:<ref>{{cite web\|url=http://www.pathologyoutlines.com/topic/smallbowelduodenitis.html\|title=Small intestine & ampulla - Inflammatory disorders - Peptic duodenitis\|author=Hasan Samra, M.D., Mohamed Mostafa, M.D.\|website=Pathology Outlines}} Topic Completed: 13 April 2020. Minor changes: 13 April 2020</ref>		Peptic injury<ref group=note>Peptic injury is also called '''peptic duodenitis''', but "duodenitis" may be reserved for cases with an inflammatory infiltrate.</ref> typically showing the following:<ref>{{cite web\|url=http://www.pathologyoutlines.com/topic/smallbowelduodenitis.html\|title=Small intestine & ampulla - Inflammatory disorders - Peptic duodenitis\|author=Hasan Samra, M.D., Mohamed Mostafa, M.D.\|website=Pathology Outlines}} Topic Completed: 13 April 2020. Minor changes: 13 April 2020</ref>
	<gallery mode=packed heights=210>		<gallery mode=packed heights=210>
	File:Histopathology of peptic duodenitis - annotated.jpg\|Brunner gland hyperplasia shows as Brunner glands above the muscularis mucosae.		File:Histopathology of peptic duodenitis - annotated.jpg\|Brunner gland hyperplasia shows as Brunner glands above the muscularis mucosae.
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	\|}		\|}

	Example in (chronic) peptic ~~duodenitis~~:		Example in (chronic) peptic injury:
	{\|class=wikitable		{\|class=wikitable
	\| (Small bowel, biopsy:) Small intestinal mucosa with histologic changes consistent with chronic peptic ~~duodenitis~~. (Negative for celiac disease.)		\| (Small bowel, biopsy:) Small intestinal mucosa with histologic changes consistent with chronic peptic injury. (Negative for celiac disease.)
	\|}		\|}
	{{Bottom}}		{{Bottom}}

Mikael Häggström:

2022-06-19T03:58:59Z

← Older revision		Revision as of 23:58, 18 June 2022
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	{{Top		<noinclude>{{Top
	\|author1=[[User:Mikael Häggström\|Mikael Häggström]]		\|author1=[[User:Mikael Häggström\|Mikael Häggström]]
	\|author2=		\|author2=
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	==Common requests==		==Common requests==
	*[[Small intestine in celiac disease]]		*[[Small intestine in celiac disease]]
			<noinclude/>
	==Microscopic examination==		==Microscopic examination==
	Generally look for:		Generally look for:

Mikael Häggström: /* Microscopic examination */ Giardia

2022-05-02T15:52:39Z

Microscopic examination: Giardia

← Older revision		Revision as of 11:52, 2 May 2022
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	*Intra-epithelial lymphocytes		*Intra-epithelial lymphocytes
	*Tumors		*Tumors
			*Giardia organisms

	===Peptic duodenitis===		===Peptic duodenitis===

Mikael Häggström: /* Others */ Giardia

2022-05-02T15:51:05Z

Others: Giardia

← Older revision		Revision as of 11:51, 2 May 2022
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	File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>,<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref> and is best evaluated at tips of villi<ref name="pmid15280404">{{cite journal\| author=Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V \| display-authors=etal\| title=Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? \| journal=J Clin Pathol \| year= 2004 \| volume= 57 \| issue= 8 \| pages= 835-9 \| pmid=15280404 \| doi=10.1136/jcp.2003.013607 \| pmc=1770380 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15280404 }} </ref>.<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>		File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>,<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref> and is best evaluated at tips of villi<ref name="pmid15280404">{{cite journal\| author=Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V \| display-authors=etal\| title=Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? \| journal=J Clin Pathol \| year= 2004 \| volume= 57 \| issue= 8 \| pages= 835-9 \| pmid=15280404 \| doi=10.1136/jcp.2003.013607 \| pmc=1770380 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15280404 }} </ref>.<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>
	File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''		File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''
			File:Histopathology of Giardia lamblia in duodenum.png\|Also take a quick look in crypts for any '''Giardia''' organisms.
	</gallery>		</gallery>

Mikael Häggström: /* Others */ Tips

2022-05-01T21:26:27Z

Others: Tips

← Older revision		Revision as of 17:26, 1 May 2022
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	===Others===		===Others===
	<gallery mode=packed heights=210>		<gallery mode=packed heights=210>
	File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>.<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref><br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>		File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>,<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref> and is best evaluated at tips of villi<ref name="pmid15280404">{{cite journal\| author=Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V \| display-authors=etal\| title=Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? \| journal=J Clin Pathol \| year= 2004 \| volume= 57 \| issue= 8 \| pages= 835-9 \| pmid=15280404 \| doi=10.1136/jcp.2003.013607 \| pmc=1770380 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15280404 }} </ref>.<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>
	File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''		File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''
	</gallery>		</gallery>

Mikael Häggström: small change

2022-04-22T22:06:08Z

small change

← Older revision		Revision as of 18:06, 22 April 2022
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	{{Endoscopic biopsies}}		{{Endoscopic biopsies}}
	==Common requests==		==Common requests==
	*[[Small intestine in celiac disease]]		*[[Small intestine in celiac disease]]

	==Microscopic examination==		==Microscopic examination==

Mikael Häggström: Format

2022-04-22T21:58:27Z

Format

← Older revision		Revision as of 17:58, 22 April 2022
Line 22:		Line 22:
	===Others===		===Others===
	<gallery mode=packed heights=210>		<gallery mode=packed heights=210>
	File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>.~~{{Image source-begin}}~~ {{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.~~{{Image source-end}}~~<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>		File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>.<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref><br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>
	File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''		File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''
	</gallery>		</gallery>

Mikael Häggström: Templated

2022-04-22T21:49:08Z

Templated

← Older revision		Revision as of 17:49, 22 April 2022
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	===Others===		===Others===
	<gallery mode=packed heights=210>		<gallery mode=packed heights=210>
	File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>.~~<ref>~~{{Image source}} {{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.~~</ref>~~<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>		File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>.{{Image source-begin}} {{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.{{Image source-end}}<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>
	File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''		File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''
	</gallery>		</gallery>

← Older revision		Revision as of 11:41, 27 November 2023
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	File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>,<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref> and is best evaluated at tips of villi<ref name="pmid15280404">{{cite journal\| author=Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V \| display-authors=etal\| title=Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? \| journal=J Clin Pathol \| year= 2004 \| volume= 57 \| issue= 8 \| pages= 835-9 \| pmid=15280404 \| doi=10.1136/jcp.2003.013607 \| pmc=1770380 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15280404 }} </ref>.<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>		File:Histopathology of duodenal intra-epithelial lymphocytes.jpg\|'''Intra-epithelial lymphocytes''' (IELs) is the main finding in '''celiac disease''' (even in earliest stage)<ref>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}</ref>,<ref group=images>{{cite journal \| vauthors = Marsh MN \|title=Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') \|journal=Gastroenterology \|volume=102 \|issue=1 \|pages=330–54 \|year=1992 \|pmid=1727768 \|doi=10.1016/0016-5085(92)91819-p}}<br>- [https://www.researchgate.net/figure/Photomicrograph-showing-increased-intraepithelial-lymphocytes-H-E-x-200cb_fig3_236066468 Figure 2- available via license: Creative Commons Attribution 2.0 Generic] license.</ref> and is best evaluated at tips of villi<ref name="pmid15280404">{{cite journal\| author=Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V \| display-authors=etal\| title=Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? \| journal=J Clin Pathol \| year= 2004 \| volume= 57 \| issue= 8 \| pages= 835-9 \| pmid=15280404 \| doi=10.1136/jcp.2003.013607 \| pmc=1770380 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15280404 }} </ref>.<br>25 - 29 IEL/100 enterocytes is considered borderline.<ref name=pathologyoutlinesceliac>{{cite web\|url=https://www.pathologyoutlines.com/topic/smallbowelceliacsprue.html\|title=Small intestine & ampulla. Malabsorption. Celiac sprue\|author=Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.\|website=Pathology Outlines\|accessdate=2022-04-04}}</ref><br> > 30 IEL/100 enterocytes represents a pathological lymphocytosis.<ref name=pathologyoutlinesceliac/>
	File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''		File:Histopathology of leiomyoma of the ileocecal valve.jpg\|'''Tumors''' (leiomyoma pictured): evaluate as per '''[[intestine with tumor]]'''
			File:Duodenal biopsy with chronic active peptic duodenitis.jpg\|The addition of a neutrophilic infiltrate in case of peptic injury confers a diagnosis of '''chronic active duodenitis'''
	File:Histopathology of Giardia lamblia in duodenum.png\|Also take a quick look in crypts for any '''Giardia''' organisms.		File:Histopathology of Giardia lamblia in duodenum.png\|Also take a quick look in crypts for any '''Giardia''' organisms.
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