Fibrocystic breast changes - Revision history

Mikael Häggström: Better

2023-10-16T21:10:26Z

Better

← Older revision		Revision as of 17:10, 16 October 2023
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	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>
	File:Histopathology of sclerosing adenosis of the breast.jpg\|'''Sclerosing adenosis''', with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.<ref name=PathologyOutlines-fibrocystic>{{cite web\|url=https://www.pathologyoutlines.com/topic/breastsclerosingadenosis.html\|title=Breast - Fibrocystic changes - Sclerosing adenosis\|author=Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.\|website=Pathology Outlines}} Topic Completed: 1 January 2015. Minor changes: 31 December 2020</ref>		File:Histopathology of sclerosing adenosis of the breast.jpg\|'''Sclerosing adenosis''', with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.<ref name=PathologyOutlines-fibrocystic>{{cite web\|url=https://www.pathologyoutlines.com/topic/breastsclerosingadenosis.html\|title=Breast - Fibrocystic changes - Sclerosing adenosis\|author=Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.\|website=Pathology Outlines}} Topic Completed: 1 January 2015. Minor changes: 31 December 2020</ref>
	File:Histopathology of a radial scar ~~of the breast~~.jpg\|A '''radial scar''' of the breast, seen as a fibroelastic stroma and entrapped glands radiating outward.		File:Histopathology of radial scar, low magnification.jpg\|A '''radial scar''' of the breast, seen as a fibroelastic stroma and entrapped glands radiating outward.
	</gallery>		</gallery>

Mikael Häggström:

2022-12-04T14:50:40Z

← Older revision		Revision as of 10:50, 4 December 2022
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	When unsure, perform immunohistochemistry for myoepithelial markers (preferably '''p63''' and '''calponin''' in breast lesions):		When unsure, perform immunohistochemistry for myoepithelial markers (preferably '''p63''' and '''calponin''' in breast lesions):
	[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a myoepithelial marker (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]		[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a myoepithelial marker (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]
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	{{Bottom}}		{{Bottom}}
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Mikael Häggström: ref

2022-06-19T21:59:02Z

ref

← Older revision		Revision as of 17:59, 19 June 2022
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	===Differential diagnosis===		===Differential diagnosis===
	Sclerosing adenosis may look similar to [[invasive ductal carcinoma]] (IDC), but IDC will:<ref name=PathologyOutlines/>		Sclerosing adenosis may look similar to [[invasive ductal carcinoma]] (IDC), but IDC will:<ref name=PathologyOutlines-fibrocystic/>
	*Not be lobular at low power		*Not be lobular at low power
	*Have marked cellular atypia		*Have marked cellular atypia

Mikael Häggström: /* Microscopic examination */ -fibrocystic

2022-06-19T21:57:03Z

Microscopic examination: -fibrocystic

← Older revision		Revision as of 17:57, 19 June 2022
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	Types:		Types:
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>
	File:Histopathology of sclerosing adenosis of the breast.jpg\|'''Sclerosing adenosis''', with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.<ref name=PathologyOutlines>{{cite web\|url=https://www.pathologyoutlines.com/topic/breastsclerosingadenosis.html\|title=Breast - Fibrocystic changes - Sclerosing adenosis\|author=Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.\|website=Pathology Outlines}} Topic Completed: 1 January 2015. Minor changes: 31 December 2020</ref>		File:Histopathology of sclerosing adenosis of the breast.jpg\|'''Sclerosing adenosis''', with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.<ref name=PathologyOutlines-fibrocystic>{{cite web\|url=https://www.pathologyoutlines.com/topic/breastsclerosingadenosis.html\|title=Breast - Fibrocystic changes - Sclerosing adenosis\|author=Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.\|website=Pathology Outlines}} Topic Completed: 1 January 2015. Minor changes: 31 December 2020</ref>
	File:Histopathology of a radial scar of the breast.jpg\|A '''radial scar''' of the breast, seen as a fibroelastic stroma and entrapped glands radiating outward.		File:Histopathology of a radial scar of the breast.jpg\|A '''radial scar''' of the breast, seen as a fibroelastic stroma and entrapped glands radiating outward.
	</gallery>		</gallery>

Mikael Häggström: heights

2022-06-19T04:01:33Z

heights

← Older revision		Revision as of 00:01, 19 June 2022
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	==Microscopic examination==		==Microscopic examination==
	Types:		Types:
	<gallery mode=packed>		<gallery mode=packed heights=220>
	File:Histopathology of sclerosing adenosis of the breast.jpg\|'''Sclerosing adenosis''', with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.<ref name=PathologyOutlines>{{cite web\|url=https://www.pathologyoutlines.com/topic/breastsclerosingadenosis.html\|title=Breast - Fibrocystic changes - Sclerosing adenosis\|author=Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.\|website=Pathology Outlines}} Topic Completed: 1 January 2015. Minor changes: 31 December 2020</ref>		File:Histopathology of sclerosing adenosis of the breast.jpg\|'''Sclerosing adenosis''', with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.<ref name=PathologyOutlines>{{cite web\|url=https://www.pathologyoutlines.com/topic/breastsclerosingadenosis.html\|title=Breast - Fibrocystic changes - Sclerosing adenosis\|author=Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.\|website=Pathology Outlines}} Topic Completed: 1 January 2015. Minor changes: 31 December 2020</ref>
	File:Histopathology of a radial scar of the breast.jpg\|A '''radial scar''' of the breast, seen as a fibroelastic stroma and entrapped glands radiating outward.		File:Histopathology of a radial scar of the breast.jpg\|A '''radial scar''' of the breast, seen as a fibroelastic stroma and entrapped glands radiating outward.

Mikael Häggström:

2022-06-19T04:00:57Z

</noinclude>

← Older revision		Revision as of 00:00, 19 June 2022
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	{{Top		<noinclude>{{Top
	\|author1=[[User:Mikael Häggström\|Mikael Häggström]]		\|author1=[[User:Mikael Häggström\|Mikael Häggström]]
	\|author2=		\|author2=
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	==Presentations==		==Presentations==
	*[[Breast biopsy or excision]]		*[[Breast biopsy or excision]]
			</noinclude>
	==Microscopic examination==		==Microscopic examination==
	Types:		Types:

Mikael Häggström: /* Differential diagnosis */ Displayed

2022-04-25T12:27:33Z

Differential diagnosis: Displayed

← Older revision		Revision as of 08:27, 25 April 2022
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	*Have no myoepithelial cells surrounding ducts.		*Have no myoepithelial cells surrounding ducts.

	When unsure, perform immunohistochemistry for '''calponin''':		When unsure, perform immunohistochemistry for myoepithelial markers (preferably '''p63''' and '''calponin''' in breast lesions):
	[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a myoepithelial marker~~{{myoepithelial marker note}}~~ (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]		[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a myoepithelial marker (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]

	{{Bottom}}		{{Bottom}}

Mikael Häggström: /* Differential diagnosis */ note

2022-02-10T13:53:37Z

Differential diagnosis: note

← Older revision		Revision as of 09:53, 10 February 2022
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	When unsure, perform immunohistochemistry for '''calponin''':		When unsure, perform immunohistochemistry for '''calponin''':
	[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a myoepithelial marker{{myoepithelial marker}} (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]		[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a myoepithelial marker{{myoepithelial marker note}} (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]

	{{Bottom}}		{{Bottom}}

Mikael Häggström: Addition

2022-02-10T13:53:05Z

Addition

← Older revision		Revision as of 09:53, 10 February 2022
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	When unsure, perform immunohistochemistry for '''calponin''':		When unsure, perform immunohistochemistry for '''calponin''':
	[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a {{myoepithelial marker}} (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]		[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a myoepithelial marker{{myoepithelial marker}} (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]

	{{Bottom}}		{{Bottom}}

Mikael Häggström: /* Differential diagnosis */ Templated

2022-02-10T13:49:54Z

Differential diagnosis: Templated

← Older revision		Revision as of 09:49, 10 February 2022
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	*Not be lobular at low power		*Not be lobular at low power
	*Have marked cellular atypia		*Have marked cellular atypia
	*Have no myoepithelial cells surrounding ~~duccts~~.		*Have no myoepithelial cells surrounding ducts.

	When unsure, perform immunohistochemistry for '''calponin''':		When unsure, perform immunohistochemistry for '''calponin''':
	[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain ~~for~~ calponin in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]		[[File:Chromogenic immunohistochemistry for calponin in sclerosing adenosis.jpg\|thumb\|center\|Immunostain with a {{myoepithelial marker}} (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.]]

	{{Bottom}}		{{Bottom}}