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	<id>https://patholines.org/index.php?action=history&amp;feed=atom&amp;title=Pancreatic_ductal_adenocarcinoma</id>
	<title>Pancreatic ductal adenocarcinoma - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://patholines.org/index.php?action=history&amp;feed=atom&amp;title=Pancreatic_ductal_adenocarcinoma"/>
	<link rel="alternate" type="text/html" href="https://patholines.org/index.php?title=Pancreatic_ductal_adenocarcinoma&amp;action=history"/>
	<updated>2026-08-20T17:16:16Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.44.2</generator>
	<entry>
		<id>https://patholines.org/index.php?title=Pancreatic_ductal_adenocarcinoma&amp;diff=7037&amp;oldid=prev</id>
		<title>Mikael Häggström: /* Microscopic evaluation on biopsies */ linebreak</title>
		<link rel="alternate" type="text/html" href="https://patholines.org/index.php?title=Pancreatic_ductal_adenocarcinoma&amp;diff=7037&amp;oldid=prev"/>
		<updated>2024-01-19T22:28:26Z</updated>

		<summary type="html">&lt;p&gt;&lt;span class=&quot;autocomment&quot;&gt;Microscopic evaluation on biopsies: &lt;/span&gt; linebreak&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 18:28, 19 January 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l11&quot;&gt;Line 11:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 11:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Make sure to also evaluate any concurrent aspiration and/or bile duct brushing.&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Make sure to also evaluate any concurrent aspiration and/or bile duct brushing.&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{further|Pancreatic tumor}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{further|Pancreatic tumor&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|linebreak=yes&lt;/ins&gt;}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;===Grading===&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;===Grading===&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Grade as follows:&amp;lt;ref&amp;gt;{{cite web|url=https://www.pathologyoutlines.com/topic/pancreasductal.html|title=Ductal adenocarcinoma, NOS|website=Pathology Outlines|author=Jennifer Vazzano, D.O., M.S., Wei Chen, M.D., Ph.D.}} Last author update: 15 June 2021&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Grade as follows:&amp;lt;ref&amp;gt;{{cite web|url=https://www.pathologyoutlines.com/topic/pancreasductal.html|title=Ductal adenocarcinoma, NOS|website=Pathology Outlines|author=Jennifer Vazzano, D.O., M.S., Wei Chen, M.D., Ph.D.}} Last author update: 15 June 2021&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Mikael Häggström</name></author>
	</entry>
	<entry>
		<id>https://patholines.org/index.php?title=Pancreatic_ductal_adenocarcinoma&amp;diff=7035&amp;oldid=prev</id>
		<title>Mikael Häggström: Not on biopsy</title>
		<link rel="alternate" type="text/html" href="https://patholines.org/index.php?title=Pancreatic_ductal_adenocarcinoma&amp;diff=7035&amp;oldid=prev"/>
		<updated>2024-01-19T22:27:20Z</updated>

		<summary type="html">&lt;p&gt;Not on biopsy&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 18:27, 19 January 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l17&quot;&gt;Line 17:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 17:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Moderately differentiated: 50 - 95% glands&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Moderately differentiated: 50 - 95% glands&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Poorly differentiated: &amp;lt; 50% glands&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Poorly differentiated: &amp;lt; 50% glands&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{Pancreatic cancer staging}}&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==Reporting==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==Reporting==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Example report:&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Example report:&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Mikael Häggström</name></author>
	</entry>
	<entry>
		<id>https://patholines.org/index.php?title=Pancreatic_ductal_adenocarcinoma&amp;diff=7033&amp;oldid=prev</id>
		<title>Mikael Häggström: Started</title>
		<link rel="alternate" type="text/html" href="https://patholines.org/index.php?title=Pancreatic_ductal_adenocarcinoma&amp;diff=7033&amp;oldid=prev"/>
		<updated>2024-01-19T22:26:15Z</updated>

		<summary type="html">&lt;p&gt;Started&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;lt;noinclude&amp;gt;{{Top&lt;br /&gt;
|author1=[[User:Mikael Häggström|Mikael Häggström]]&lt;br /&gt;
|author2=&lt;br /&gt;
}}&lt;br /&gt;
==Presentation==&lt;br /&gt;
*[[Pancreatic tumor]]&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;&lt;br /&gt;
==Microscopic evaluation on biopsies==&lt;br /&gt;
[[File:Histopathology of pancreatic ductal adenocarcinoma.jpg|thumb|Histopathology of pancreatic ductal adenocarcinoma]]&lt;br /&gt;
The main findings are glands formations with atypical epithelial cells and desmoplasia. If histology, clinical history and radiology are consistent, then no further immunohistochemistry or other molecular workup is needed for the diagnosis.&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Make sure to also evaluate any concurrent aspiration and/or bile duct brushing.&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
{{further|Pancreatic tumor}}&lt;br /&gt;
===Grading===&lt;br /&gt;
Grade as follows:&amp;lt;ref&amp;gt;{{cite web|url=https://www.pathologyoutlines.com/topic/pancreasductal.html|title=Ductal adenocarcinoma, NOS|website=Pathology Outlines|author=Jennifer Vazzano, D.O., M.S., Wei Chen, M.D., Ph.D.}} Last author update: 15 June 2021&amp;lt;/ref&amp;gt;&lt;br /&gt;
*Well differentiated: &amp;gt; 95% tumor composed of glands&lt;br /&gt;
*Moderately differentiated: 50 - 95% glands&lt;br /&gt;
*Poorly differentiated: &amp;lt; 50% glands&lt;br /&gt;
{{Pancreatic cancer staging}}&lt;br /&gt;
==Reporting==&lt;br /&gt;
Example report:&lt;br /&gt;
{|class=wikitable&lt;br /&gt;
| A. Pancreas, core biopsy:&lt;br /&gt;
*Pancreatic ductal adenocarcinoma, moderately differentiated.&lt;br /&gt;
Comment: Note is made of concurrent aspiration cytology (DN-12-1234), which is positive for adenocarcinoma.&lt;br /&gt;
|}&lt;br /&gt;
&amp;lt;noinclude&amp;gt;{{Bottom}}&amp;lt;/noinclude&amp;gt;&lt;/div&gt;</summary>
		<author><name>Mikael Häggström</name></author>
	</entry>
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