Skin lesions - Revision history

Mikael Häggström: Generalized

2019-09-17T09:01:09Z

Generalized

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	~~{{Top~~		#REDIRECT [[Skin]]
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	~~==Fixation==~~
	*Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>
	*Immunofluorescence: For example Michel's solution<ref name=kvast/><ref group="notes">Minimally consisting of ammonium sulfate and saline.<br>- {{cite journal\|last1=Niedecken\|first1=Heinz W.\|last2=Lange\|first2=Claus-Ekkehard\|title=Simplified fixative medium for direct immunofluorescence in skin biopsies\|journal=Journal of the American Academy of Dermatology\|volume=12\|issue=5\|year=1985\|pages=828–831\|issn=01909622\|doi=10.1016/S0190-9622(85)70103-X}}</ref>
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Mikael Häggström: small edit to update template

2019-09-09T15:08:31Z

small edit to update template

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	*Immunofluorescence: For example Michel's solution<ref name=kvast/><ref group="notes">Minimally consisting of ammonium sulfate and saline.<br>- {{cite journal\|last1=Niedecken\|first1=Heinz W.\|last2=Lange\|first2=Claus-Ekkehard\|title=Simplified fixative medium for direct immunofluorescence in skin biopsies\|journal=Journal of the American Academy of Dermatology\|volume=12\|issue=5\|year=1985\|pages=828–831\|issn=01909622\|doi=10.1016/S0190-9622(85)70103-X}}</ref>		*Immunofluorescence: For example Michel's solution<ref name=kvast/><ref group="notes">Minimally consisting of ammonium sulfate and saline.<br>- {{cite journal\|last1=Niedecken\|first1=Heinz W.\|last2=Lange\|first2=Claus-Ekkehard\|title=Simplified fixative medium for direct immunofluorescence in skin biopsies\|journal=Journal of the American Academy of Dermatology\|volume=12\|issue=5\|year=1985\|pages=828–831\|issn=01909622\|doi=10.1016/S0190-9622(85)70103-X}}</ref>
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Mikael Häggström: /

2019-09-09T15:06:16Z

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	==Fixation==		==Fixation==
	*Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>		*Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>
	*Immunofluorescence: For example Michel's solution<ref name=kvast/><ref group="notes">Minimally consisting of ammonium sulfate and saline.<br>- {{cite journal\|last1=Niedecken\|first1=Heinz W.\|last2=Lange\|first2=Claus-Ekkehard\|title=Simplified fixative medium for direct immunofluorescence in skin biopsies\|journal=Journal of the American Academy of Dermatology\|volume=12\|issue=5\|year=1985\|pages=828–831\|issn=01909622\|doi=10.1016/S0190-9622(85)70103-X}}		*Immunofluorescence: For example Michel's solution<ref name=kvast/><ref group="notes">Minimally consisting of ammonium sulfate and saline.<br>- {{cite journal\|last1=Niedecken\|first1=Heinz W.\|last2=Lange\|first2=Claus-Ekkehard\|title=Simplified fixative medium for direct immunofluorescence in skin biopsies\|journal=Journal of the American Academy of Dermatology\|volume=12\|issue=5\|year=1985\|pages=828–831\|issn=01909622\|doi=10.1016/S0190-9622(85)70103-X}}</ref>
	{{Fixation}}		{{Fixation}}

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Mikael Häggström: +Solution

2019-09-09T15:06:01Z

+Solution

← Older revision		Revision as of 11:06, 9 September 2019
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	==Fixation==		==Fixation==
	*Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>		*Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>
	*Immunofluorescence: For example Michel's solution<ref name=kvast/>		*Immunofluorescence: For example Michel's solution<ref name=kvast/><ref group="notes">Minimally consisting of ammonium sulfate and saline.<br>- {{cite journal\|last1=Niedecken\|first1=Heinz W.\|last2=Lange\|first2=Claus-Ekkehard\|title=Simplified fixative medium for direct immunofluorescence in skin biopsies\|journal=Journal of the American Academy of Dermatology\|volume=12\|issue=5\|year=1985\|pages=828–831\|issn=01909622\|doi=10.1016/S0190-9622(85)70103-X}}
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Mikael Häggström: Bullet

2019-09-09T15:03:04Z

Bullet

← Older revision		Revision as of 11:03, 9 September 2019
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	==Fixation==		==Fixation==
	Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>		*Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>
	*Immunofluorescence: For example Michel's solution<ref name=kvast/>		*Immunofluorescence: For example Michel's solution<ref name=kvast/>
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Mikael Häggström: Removed

2019-09-09T13:09:36Z

Removed

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Mikael Häggström: Temporarily removed

2019-09-09T13:09:14Z

Temporarily removed

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Mikael Häggström: small edit to update template

2019-09-09T13:07:34Z

small edit to update template

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	I. Table of Contents 2 II. Instructions for the sampler handling the sample 2		I. Table of Contents 2 II. Instructions for the sampler handling the sample 2

Mikael Häggström: Url

2019-09-09T12:59:52Z

Url

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	==Fixation==		==Fixation==
	Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>		Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web\|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf\|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision\|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel\|accessdate=2019-09-09\|website=KVAST (Swedish Society of Pathology)}}</ref>
	*Immunofluorescence: For example Michel's solution<ref name=kvast/>		*Immunofluorescence: For example Michel's solution<ref name=kvast/>
	{{Fixation}}		{{Fixation}}

Mikael Häggström: Started

2019-09-09T12:54:23Z

Started

New page

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I. Table of Contents 2 II. Instructions for the sampler handling the sample 2
III. Anamnestic referral information 2
IV. Cutting principles 2
1. General cut-out instructions 2
2. Punch biopsies 3
3. Curettage 3
4. Plan or tangential excision ('shave') 3
5. Skin Excisions 3
6. Wedge sections 4
7. Extended Excisions 4
8. Polypoid lesions 5
9. Subcutaneous preparations 5 V. Section 5
WE. Summary 5

==Fixation==
Standard examination: Buffered 4% formaldehyde.<ref name=kvast>{{cite web|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision|author=Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel|accessdate=2019-09-09|website=KVAST (Swedish Society of Pathology)}}</ref>
*Immunofluorescence: For example Michel's solution<ref name=kvast/>
{{Fixation}}
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3. Specimen vessels shall be labeled with the patient's name, social security number, anatomical location and the nature of the specimen (size of punch biopsy shall be indicated). If several samples are taken at the same time, these should be numbered.
III. Anamnestic referral information
1. Relevant information on medical history. Clinical description of the change (s) (anatomical location, number, distribution, color, size, configuration).
2. Relevant previous PAD.
3. Nature of the prepathesis: punch biopsy (size should be specified), skin scratching (curretage), plane or tangential excision (shave), skin excision, wedge resection, dilated excision, subcutaneous preparation.
Possible suture markings.
4. Clinical diagnosis and questioning.
2
IV. Utskärningsprinciper
1. General cut-out instructions
All preparations, and any changes, are preferably measured and described with a sketch.
Touch to mark resection surfaces, especially if the change is diffusely delimited.
Specify how the cut is made. Use Arabic numerals to mark fractions if the sample includes more than one preparation. Use letters to mark embedded disks.
Indicate whether material is saved, preferably with + on the sketch.
2. Punch biopsies
10 mm punch biopsies are treated as oval skin excision.
3. Skin scraping (curettage)
Enter approximate amount.
Embed everything.
4. Plan or tangential excision ('shave')
5. Skin excisions
A. Non-sutured oval excisions
a. Change <15 mm
Well delimited - embed the whole change in the form of cross-sections as below.
Indicate whether material is saved, preferably with + on the sketch.
9 - 15 mm
+
+
<5 mm
Embed in full and orient so that the incisions are perpendicular to the skin surface.
If a clear change, orient the preparation so that the smallest margin to the resection surface can be assessed.
<5 mm
Embed on edge so that the incisions are perpendicular to the skin surface.
<4 mm
+
+
4 - 8 mm
5 - 8 mm
Divide, embed with dividing surfaces down.
If a clear change, orient the preparation so that the smallest margin to the resection surface can be assessed.
NOTE! Shared punch biopsies should not be trimmed.
+
≥ 5 mm
Slab, embedded on edge representative slabs.
+
+
3
Diffused delimited - embed the entire change in the form of cross-sections as below, embed the end pieces.
b. Change> 15 mm, regardless of appearance - special cut.
Embed relevant parts of the change in the form of cross-sections taken where the margin to the resection surface is the least. Optionally embed the end pieces.
B. Suture labeled skin preparations
Suture labeled skin preparations should be documented with a sketch.
Mark at least one resection surface with color and indicate on the sketch.
Embed the entire change and end pieces, preferably in the form of individual discs.
End pieces may be needed. is excluded if a well-defined change.
Exception: larger resectates that may be treated individually.
6. Wedge sections
Wedge sections should be oriented and documented in sketch. Select the two resection surfaces with different colors.
Divide, embed with dividing surfaces down.
+
+
A
B
C
B
C
D
A
A
E
B
C
A
A
E
D
<4 mm
4 - 8 mm
9 - 15 mm
Disc so that the entire resection area is represented. Embed with dividing surfaces facing down. NOTE! If the preparation is very irregular at the edges and it is not possible with whole disc from the resection surface take parallel vertical or horizontal discs.
≤ 8 mm
A
B
> 8 mm
A
B
D
C
B
C
D
E
A
4
7. Extended excisions
A. Previously NOT radically removed malignant tumor
a. scars ≤ 20 mm
Embed the entire scar in the form of transverse discs and marks with under-marking. This also applies to suture-marked preparation, which is documented with sketch.
b. scars> 20 mm - special cut
B. Previously RADICALLY removed malignant melanoma
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