Template:Esophagitis: Difference between revisions
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[[File:Histopathology of acute and chronic inflammation of the gastro-esophageal junction, annotated.jpg|thumb|190px|GE junction with chronic '''esophagitis''', including plasma cells (black arrow), an acute inflammation with neutrophils (white arrow), as well as basal layer hyperplasia (yellow double-headed arrow).]] | [[File:Histopathology of acute and chronic inflammation of the gastro-esophageal junction, annotated.jpg|thumb|190px|GE junction with chronic '''esophagitis''', including plasma cells (black arrow), an acute inflammation with neutrophils (white arrow), as well as basal layer hyperplasia (yellow double-headed arrow).]] | ||
Look for signs of (reflux) '''esophagitis''', mainly:<ref name=PathologyOutlinesEsophagitis>{{cite web|url=http://www.pathologyoutlines.com/topic/esophagusreflux.html|title=Esophagus - Esophagitis - Reflux esophagitis / gastroesophageal reflux disease|author=Elliot Weisenberg|website=Pathology Outlines}} Topic Completed: 1 October 2012. Minor changes: 8 July 2020</ref> | Look for signs of (reflux) '''esophagitis''', mainly:<ref name=PathologyOutlinesEsophagitis>{{cite web|url=http://www.pathologyoutlines.com/topic/esophagusreflux.html|title=Esophagus - Esophagitis - Reflux esophagitis / gastroesophageal reflux disease|author=Elliot Weisenberg|website=Pathology Outlines}} Topic Completed: 1 October 2012. Minor changes: 8 July 2020</ref> | ||
*'''Inflammatory cells''', especially when intra-epithelial. Neutrophils confer a diagnosis of acute inflammation, while plasma cells, eosinophils and excess T cells confer a diagnosis of chronic inflammation. | *'''Inflammatory cells''', especially when intra-epithelial. Neutrophils confer a diagnosis of acute inflammation, while plasma cells, eosinophils and excess T cells confer a diagnosis of chronic inflammation. In eosinophil-predominant inflammation, also evaluate as suspected '''[[eosinophilic esophagitis]]'''. | ||
*'''Basal cell hyperplasia''' exceeding 15 - 20% of the epithelial thickness. | *'''Basal cell hyperplasia''' exceeding 15 - 20% of the epithelial thickness. | ||
*'''Stromal papillae''' reaching upper third of the epithelium. | *'''Stromal papillae''' reaching upper third of the epithelium. | ||
*'''Loss of orientation''' of superficial epithelial cells. | |||
*'''Ballooned squamous cells''' | *'''Ballooned squamous cells''' | ||
<gallery> | <gallery> | ||
File:Histology of an eosinophil in esophageal epithelium.jpg|thumb|180px|An intra-epithelial '''eosinophil''' (characterized by its bilobed nucleus despite scant visible eosinophilic cytoplasm) | File:Histology of an eosinophil in esophageal epithelium.jpg|thumb|180px|An intra-epithelial '''eosinophil''' (characterized by its bilobed nucleus despite scant visible eosinophilic cytoplasm) | ||
</gallery> | </gallery> | ||
Latest revision as of 15:44, 10 December 2020
Esophagitis
Look for signs of (reflux) esophagitis, mainly:[1]
- Inflammatory cells, especially when intra-epithelial. Neutrophils confer a diagnosis of acute inflammation, while plasma cells, eosinophils and excess T cells confer a diagnosis of chronic inflammation. In eosinophil-predominant inflammation, also evaluate as suspected eosinophilic esophagitis.
- Basal cell hyperplasia exceeding 15 - 20% of the epithelial thickness.
- Stromal papillae reaching upper third of the epithelium.
- Loss of orientation of superficial epithelial cells.
- Ballooned squamous cells
-
An intra-epithelial eosinophil (characterized by its bilobed nucleus despite scant visible eosinophilic cytoplasm)
- ↑ Elliot Weisenberg. Esophagus - Esophagitis - Reflux esophagitis / gastroesophageal reflux disease. Pathology Outlines. Topic Completed: 1 October 2012. Minor changes: 8 July 2020