Template:Cervical dysplasia: Difference between revisions

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{| class="wikitable"
{{Edit|Template:Cervical dysplasia}}<br>
|+ Cervical intraepithelial neoplasia {{Edit|Template:CIN grades}}
Look for '''[[cervical dysplasia]]'''. It is mainly seen as nuclei with hyperchromasia, coarse chromatin and irregular contours.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/cervixHSILCINIII.html|title=HSIL / CIN II / CIN III|website=PathologyOutlines|author=Khaled J. Alkhateeb, M.B.B.S., Ziyan T. Salih, M.D.}} Topic Completed: 29 March 2021. Minor changes: 9 February 2022</ref>
|-
! Histology Grade
! Corresponding Cytology
! Description
! Image
|-
|'''CIN 1''' (Grade I)
|Low-grade squamous intraepithelial lesion (LSIL)
|
* Mild epithelial dysplasia
* Confined to the basal 1/3 of the epithelium
|[[File:LSIL (CIN 1), Cervical Biopsy (3776284166).jpg|200px]]
|-
|'''CIN 2/3'''
|High-grade squamous intraepithelial lesion (HSIL)<ref group="notes">HSIL+ encompasses HSIL, AGC, and cancer</ref>
|
* Represents a mix of low and high-grade lesions not easily differentiated by histology
|
|-
|'''CIN 2''' (Grade II)<ref group="notes">CIN 2+ encompasses CIN 2, CIN 3, adenocarcinoma in situ (AIS), and cancer</ref>
|
|
* Moderate dysplasia confined to the basal 2/3 of the epithelium
|
|-
|'''CIN 3''' (Grade III)<ref group="notes">CIN 3+ encompasses CIN 3, AIS, and cancer</ref>
|
|
* Severe dysplasia with undifferentiated neoplastic cells that span more than 2/3 of the epithelium
* May involve the full thickness
* May also be referred to as cervical carcinoma in situ
| [[File:Histopathology of CIN 3.jpg|200px]]
|}
<gallery mode=packed heights=190px>
<gallery mode=packed heights=190px>
File:Spectrum of SIL cervical dysplasia.png|Spectrum from normal to high grade SIL
File:Spectrum of SIL cervical dysplasia.png|Spectrum from normal to high grade SIL.<ref>Source image by Ed Uthman from Houston, TX, USA. {{CC-BY 2.0 inline}}</ref>
File:Histopathology of CIN 3 with endocervical gland invasion.jpg|'''Endocervical gland invasion''' is associated with high-grade lesions.<ref name="NagiSchlosshauer2006">{{cite journal|last1=Nagi|first1=Chandandeep S.|last2=Schlosshauer|first2=Peter W.|title=Endocervical glandular involvement is associated with high-grade SIL|journal=Gynecologic Oncology|volume=102|issue=2|year=2006|pages=240–243|issn=00908258|doi=10.1016/j.ygyno.2005.12.029}}</ref>
</gallery>
</gallery>
{{Further|Cervical dysplasia}}
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Latest revision as of 13:41, 2 April 2022

edit
Look for cervical dysplasia. It is mainly seen as nuclei with hyperchromasia, coarse chromatin and irregular contours.[1]

  • Spectrum from normal to high grade SIL.[2]
    Spectrum from normal to high grade SIL.[2]

Further information: Cervical dysplasia

Notes


Main page

References

  1. ↑ Khaled J. Alkhateeb, M.B.B.S., Ziyan T. Salih, M.D.. HSIL / CIN II / CIN III. PathologyOutlines. Topic Completed: 29 March 2021. Minor changes: 9 February 2022
  2. ↑ Source image by Ed Uthman from Houston, TX, USA. Creative Commons Attribution 2.0 Generic (CC BY 2.0) license

Image sources


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