Fundic gland polyp: Difference between revisions

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Mikael Häggström (talk | contribs)
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#REDIRECT [[Gastric polyp]]
<noinclude>{{Top
|author1=[[User:Mikael Häggström|Mikael Häggström]]
|author2=
}}
==Presentation==
*Mainly '''[[gastric polyp]]'''.
</noinclude>
==Microscopic evaluation==
<gallery mode=packed heights=200>
File:Histopathology of fundic gland polyp, high magnification, annotated.jpg|thumb|A '''[[fundic gland polyp]]''' displays cystically dilated glands lined by chief cells and parietal cells, and possibly also mucinous foveolar cells.<ref name=PathologyOutlines-fundic-gland>{{cite web|url=https://www.pathologyoutlines.com/topic/stomachfundicgland.html|title=Stomach Polyps - Fundic gland polyp|website=PathologyOutlines|author=Naziheh Assarzadegan, M.D., Raul S. Gonzalez, M.D.}} Topic Completed: 1 November 2017. Minor changes: 11 December 2019</ref>
File:Histopathology of a fundic glad polyp, low magnification.jpg|thumb|A '''[[fundic gland polyp]]''', low magnification.{{MH}}
</gallery>
 
===Differential diagnosis===
<gallery mode=packed heights=200>
File:Histopathology of a gastric hyperplastic polyp.jpg|Gastric '''hyperplastic polyp''': Elongated, tortuous, and cystic foveolae separated by edematous and inflamed stroma.<ref>{{cite journal|last1=Groisman|first1=Gabriel M.|last2=Depsames|first2=Roman|last3=Ovadia|first3=Baruch|last4=Meir|first4=Alona|title=Metastatic Carcinoma Occurring in a Gastric Hyperplastic Polyp Mimicking Primary Gastric Cancer: The First Reported Case|journal=Case Reports in Pathology|volume=2014|year=2014|pages=1–5|issn=2090-6781|doi=10.1155/2014/781318}}<br>- [http://creativecommons.org/licenses/by/3.0/ Attribution 3.0 Unported (CC BY 3.0) license]</ref>
File:Histopathology of a gastric hyperplastic polyp, high magnification.jpg|Gastric '''hyperplastic polyp''', high magnification, showing the edematous and inflamed stroma.
</gallery>
 
==Workup==
<gallery mode=packed heights=200>
File:Histopathology of a fundic gland polyp with dysplasia.jpg|Look for '''dysplasia''' (center), compared to normal mucosa (at right). {{MH}}
</gallery>
Dysplasia in fundic gland polyp is mainly seen as nuclear enlargement, hyperchromasia, pseudostratification, and loss of cytoplasmic mucin.<ref name="pmid26386080">{{cite journal| author=Levy MD, Bhattacharya B| title=Sporadic Fundic Gland Polyps With Low-Grade Dysplasia: A Large Case Series Evaluating Pathologic and Immunohistochemical Findings and Clinical Behavior. | journal=Am J Clin Pathol | year= 2015 | volume= 144 | issue= 4 | pages= 592-600 | pmid=26386080 | doi=10.1309/AJCPGK8QTYPUQJYL | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26386080  }} </ref> However, you don't need to spend much effort in the decision, since these patients have an excellent prognosis whether there is dysplasia or not.
 
==Reporting==
Generally, keep it short:
{|class=wikitable
| (Stomach, excision:)<br>'''Fundic gland polyp'''
|}<noinclude>
{{Bottom}}</noinclude>

Latest revision as of 19:29, 2 December 2022

Author: Mikael Häggström [note 1]

Presentation

Microscopic evaluation

Differential diagnosis

Workup

Dysplasia in fundic gland polyp is mainly seen as nuclear enlargement, hyperchromasia, pseudostratification, and loss of cytoplasmic mucin.[3] However, you don't need to spend much effort in the decision, since these patients have an excellent prognosis whether there is dysplasia or not.

Reporting

Generally, keep it short:

(Stomach, excision:)
Fundic gland polyp

Notes

  1. ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. ↑ Naziheh Assarzadegan, M.D., Raul S. Gonzalez, M.D.. Stomach Polyps - Fundic gland polyp. PathologyOutlines. Topic Completed: 1 November 2017. Minor changes: 11 December 2019
  2. ↑ Groisman, Gabriel M.; Depsames, Roman; Ovadia, Baruch; Meir, Alona (2014). "Metastatic Carcinoma Occurring in a Gastric Hyperplastic Polyp Mimicking Primary Gastric Cancer: The First Reported Case ". Case Reports in Pathology 2014: 1–5. doi:10.1155/2014/781318. ISSN 2090-6781. 
    - Attribution 3.0 Unported (CC BY 3.0) license
  3. ↑ Levy MD, Bhattacharya B (2015). "Sporadic Fundic Gland Polyps With Low-Grade Dysplasia: A Large Case Series Evaluating Pathologic and Immunohistochemical Findings and Clinical Behavior. ". Am J Clin Pathol 144 (4): 592-600. doi:10.1309/AJCPGK8QTYPUQJYL. PMID 26386080. Archived from the original. . 

Image sources

  1. ↑ 1.0 1.1 Image(s) by: Mikael Häggström, M.D. Public Domain
    - Author info
    - Reusing images
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