Template:Gross processing of skin excisions: Difference between revisions

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==Gross processing of skin excisions==
=={{#if: {{{header|}}}
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  | Gross processing of skin excisions
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{|class="wikitable"
{|class="wikitable"
|+ Gross pathologic processing of skin excisions<ref name=processing>
|+ Gross pathologic processing of skin excisions<ref name=processing>There are many variants for the processing of skin excisions. These examples use aspects from the following sources:
*{{cite web|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision|website=Swedish Society of Pathology}}<br>- For number of slices and coverage of lesions, as well as including sections from each edge in case of diffuse border.
*{{cite web|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision|website=Swedish Society of Pathology}}<br>- For number of slices and coverage of lesions, depending on size.
*{{cite web|url=http://www.svfp.se/stora_utskarningen|title=Stora utskärningen|website=KVAST (Swedish Society of Pathology)|author=Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg|accessdate=2019-09-26}}<br>- For slices towards the tips to determine radicality, which can be parallel to the slices through the lesions (shown), or as longitudinal slices that go through each tip.
*{{cite web|url=http://pathology.ucla.edu/workfiles/Education/Residency%20Program/Gross%20Manual/SkinExcisionLarge.pdf|title=Dermatopathology Grossing Guidelines|website=University of California, Los Angeles|accessdate=2019-10-23}}<br>- For microtomy of the most central side at the lesion
*{{cite web|url=http://pathology.ucla.edu/workfiles/Education/Residency%20Program/Gross%20Manual/SkinExcisionLarge.pdf|title=Dermatopathology Grossing Guidelines|website=University of California, Los Angeles|accessdate=2019-10-23}}<br>- For microtomy of the most central side at the lesion
*{{cite journal |vauthors=Finley EM |title=The principles of mohs micrographic surgery for cutaneous neoplasia |journal=Ochsner J |volume=5 |issue=2 |pages=22–33 |date=2003 |pmid=22826680 |pmc=3399331 |doi= |url=http://www.ochsnerjournal.org/content/5/2/22}}<br>- With a "standard histologic examination" that, in addition to the lesion, only includes one section from each side along the longest diameter of the specimen. <br>- It also shows an example of circular coverage, with equal coverage distance in all four directions. <br>- The entire specimen may be submitted if the risk of malignancy is high.</ref>
*{{cite journal |vauthors=Finley EM |title=The principles of mohs micrographic surgery for cutaneous neoplasia |journal=Ochsner J |volume=5 |issue=2 |pages=22–33 |date=2003 |pmid=22826680 |pmc=3399331 |doi= |url=http://www.ochsnerjournal.org/content/5/2/22}}<br>- With a "standard histologic examination" that, in addition to the lesion, only includes one section from each side along the longest diameter of the specimen. <br>- It also shows an example of circular coverage, with equal coverage distance in all four directions. <br>- The entire specimen may be submitted if the risk of malignancy is high.</ref><ref group="note">The excision examples show a normal mole (upper row, benign appearance) and a superficial basal cell carcinoma (lower row, suspected malignancy).</ref>
!rowspan=2|  !!colspan=3| Lesion size
!rowspan=2|  !!colspan=3| Lesion size
|-
|-
! <4 mm !! 4 - 8 mm !! 9 - 15 mm
! <4 mm !! 4 - 8 mm !! 9 - 15 mm
|-
|-
! Well-defined border
! Benign appearance
|  
|  
[[File:Tissue selection from skin excision less than 4 mm with well-defined lesion.png|220px]]
[[File:Tissue selection from skin excision with lesion less than 4 mm with benign appearance.png|220px]]
|  
|  
[[File:Tissue selection from skin excision 4-8 mm with well-defined lesion.png|220px]]
[[File:Tissue selection from skin excision with lesion 4-8 mm with benign appearance.png|220px]]
|  
|  
[[File:Tissue selection from skin excision 9-15 mm with well-defined lesion.png|220px]]
[[File:Tissue selection from skin excision with lesion 9-15 mm with benign appearance.png|220px]]
|-
|-
! Diffuse border
! Suspected malignancy
| [[File:Tissue selection from skin excision less than 4 mm with diffuse lesion.png|220px]]
| [[File:Tissue selection from skin excision less than 4 mm with suspected malignant lesion.png|220px]]
| [[File:Tissue selection from skin excision 4-8 mm with diffuse lesion.png|220px]]
| [[File:Tissue selection from skin excision 4-8 mm with suspected malignant lesion.png|220px]]
| [[File:Tissue selection from skin excision 9-15 mm with diffuse lesion.png|220px]]
| [[File:Tissue selection from skin excision 9-15 mm with suspected malignant lesion.png|220px]]
|}
|}
In table above, each top image shows recommended lines for cutting out slices to be submitted for further processing. Bottom image shows which side of the slice that should be put to microtomy. Dashed lines here mean that either side could be used.
In table above, each top image shows recommended lines for cutting out slices to be submitted for further processing. Bottom image shows which side of the slice that should be put to microtomy. Dashed lines here mean that either side could be used.
 
{{#ifeq: {{PAGENAME}} | Gross processing of skin excisions |  | {{Further|Gross processing of skin excisions}}  }}<noinclude>
Up to the entire specimen may be sliced and submitted if the risk of malignancy is high.<ref name=processing/> Otherwise the rest may be saved in case microscopy indicates further sampling.
==See also==
*[[Template:Gross processing of suspected malignant skin lesions]]
*[[Template:Gross processing of skin lesions with benign appearance]]
*[[Gross processing of skin excisions]]
{{Bottom}}
</noinclude>

Latest revision as of 12:16, 24 October 2023

Gross processing of skin excisions

Gross pathologic processing of skin excisions[1][note 1]
Lesion size
<4 mm 4 - 8 mm 9 - 15 mm
Benign appearance

File:Tissue selection from skin excision with lesion less than 4 mm with benign appearance.png

File:Tissue selection from skin excision with lesion 4-8 mm with benign appearance.png

File:Tissue selection from skin excision with lesion 9-15 mm with benign appearance.png

Suspected malignancy File:Tissue selection from skin excision less than 4 mm with suspected malignant lesion.png File:Tissue selection from skin excision 4-8 mm with suspected malignant lesion.png File:Tissue selection from skin excision 9-15 mm with suspected malignant lesion.png

In table above, each top image shows recommended lines for cutting out slices to be submitted for further processing. Bottom image shows which side of the slice that should be put to microtomy. Dashed lines here mean that either side could be used.

See also

Notes

  1. The excision examples show a normal mole (upper row, benign appearance) and a superficial basal cell carcinoma (lower row, suspected malignancy).

Main page

References

  1. There are many variants for the processing of skin excisions. These examples use aspects from the following sources: ". Ochsner J 5 (2): 22–33. 2003. PMID 22826680. PMC: 3399331. Archived from the original. . 
    - With a "standard histologic examination" that, in addition to the lesion, only includes one section from each side along the longest diameter of the specimen.
    - It also shows an example of circular coverage, with equal coverage distance in all four directions.
    - The entire specimen may be submitted if the risk of malignancy is high.

Image sources