Urothelial versus squamous-cell carcinoma: Difference between revisions

From patholines.org
Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
Mikael Häggström (talk | contribs)
Administrators, Editors, Image-reviewer, csmoderator, Interface administrators, Administrators, Upload Wizard campaign editors
7,148 edits
Mikael Häggström (talk | contribs)
Administrators, Editors, Image-reviewer, csmoderator, Interface administrators, Administrators, Upload Wizard campaign editors
7,148 edits
Line 16: Line 16:
</gallery>
</gallery>


In uncertain cases, perform immunohistochemistry for '''S100P''' and '''GATA3''', where positivity indicates urothelial carcinomas with squamous differentiation (positive in 83% and 35% respectively), and negativity indicates squamous cell carcinomas (present in 9% and near-0%, respectively).<ref name="GulmannPaner2013">{{cite journal|last1=Gulmann|first1=Christian|last2=Paner|first2=Gladell P.|last3=Parakh|first3=Rugvedita S.|last4=Hansel|first4=Donna E.|last5=Shen|first5=Steven S.|last6=Ro|first6=Jae Y.|last7=Annaiah|first7=Chandrakanth|last8=Lopez-Beltran|first8=Antonio|last9=Rao|first9=Priya|last10=Arora|first10=Komal|last11=Cho|first11=Yong|last12=Herrera-Hernandez|first12=Loren|last13=Alsabeh|first13=Randa|last14=Amin|first14=Mahul B.|title=Immunohistochemical profile to distinguish urothelial from squamous differentiation in carcinomas of urothelial tract|journal=Human Pathology|volume=44|issue=2|year=2013|pages=164–172|issn=00468177|doi=10.1016/j.humpath.2012.05.018}}</ref>
In uncertain cases, perform immunohistochemistry for '''S100P''' and '''GATA3''', where positivity indicates urothelial carcinomas with squamous differentiation (positive in 83% and 35% respectively), and negativity indicates squamous cell carcinomas (positive in 9% and near-0%, respectively).<ref name="GulmannPaner2013">{{cite journal|last1=Gulmann|first1=Christian|last2=Paner|first2=Gladell P.|last3=Parakh|first3=Rugvedita S.|last4=Hansel|first4=Donna E.|last5=Shen|first5=Steven S.|last6=Ro|first6=Jae Y.|last7=Annaiah|first7=Chandrakanth|last8=Lopez-Beltran|first8=Antonio|last9=Rao|first9=Priya|last10=Arora|first10=Komal|last11=Cho|first11=Yong|last12=Herrera-Hernandez|first12=Loren|last13=Alsabeh|first13=Randa|last14=Amin|first14=Mahul B.|title=Immunohistochemical profile to distinguish urothelial from squamous differentiation in carcinomas of urothelial tract|journal=Human Pathology|volume=44|issue=2|year=2013|pages=164–172|issn=00468177|doi=10.1016/j.humpath.2012.05.018}}</ref>


{{Bottom}}
{{Bottom}}

Revision as of 13:34, 5 February 2021

Author: Mikael Häggström [note 1]

Gross processing

Microscopic examination

In uncertain cases, perform immunohistochemistry for S100P and GATA3, where positivity indicates urothelial carcinomas with squamous differentiation (positive in 83% and 35% respectively), and negativity indicates squamous cell carcinomas (positive in 9% and near-0%, respectively).[1]

Notes

  1. ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. ↑ Gulmann, Christian; Paner, Gladell P.; Parakh, Rugvedita S.; Hansel, Donna E.; Shen, Steven S.; Ro, Jae Y.; Annaiah, Chandrakanth; Lopez-Beltran, Antonio; et al. (2013). "Immunohistochemical profile to distinguish urothelial from squamous differentiation in carcinomas of urothelial tract ". Human Pathology 44 (2): 164–172. doi:10.1016/j.humpath.2012.05.018. ISSN 00468177. 

Image sources


Retrieved from "https://patholines.org/index.php?title=Urothelial_versus_squamous-cell_carcinoma&oldid=3120"