Template:Cervical dysplasia: Difference between revisions

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Spectrum
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File:Spectrum of SIL cervical dysplasia.png|Spectrum from normal to high grade SIL
File:Spectrum of SIL cervical dysplasia.png|Spectrum from normal to high grade SIL.<ref>Source image by Ed Uthman from Houston, TX, USA. {{CC-BY 2.0 inline}}</ref>
File:Histopathology of CIN 3 with endocervical gland invasion.jpg|'''Endocervical gland invasion''' is associated with high-grade lesions.<ref name="NagiSchlosshauer2006">{{cite journal|last1=Nagi|first1=Chandandeep S.|last2=Schlosshauer|first2=Peter W.|title=Endocervical glandular involvement is associated with high-grade SIL|journal=Gynecologic Oncology|volume=102|issue=2|year=2006|pages=240–243|issn=00908258|doi=10.1016/j.ygyno.2005.12.029}}</ref>
File:Histopathology of CIN 3 with endocervical gland invasion.jpg|'''Endocervical gland invasion''' is associated with high-grade lesions.<ref name="NagiSchlosshauer2006">{{cite journal|last1=Nagi|first1=Chandandeep S.|last2=Schlosshauer|first2=Peter W.|title=Endocervical glandular involvement is associated with high-grade SIL|journal=Gynecologic Oncology|volume=102|issue=2|year=2006|pages=240–243|issn=00908258|doi=10.1016/j.ygyno.2005.12.029}}</ref>
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Revision as of 08:55, 1 February 2022

Cervical intraepithelial neoplasia edit
Histology Grade Corresponding Cytology Description Image
CIN 1 (Grade I) Low-grade squamous intraepithelial lesion (LSIL)
  • Mild epithelial dysplasia
  • Confined to the basal 1/3 of the epithelium
File:LSIL (CIN 1), Cervical Biopsy (3776284166).jpg
CIN 2/3 High-grade squamous intraepithelial lesion (HSIL)[notes 1]
  • Represents a mix of low and high-grade lesions not easily differentiated by histology
CIN 2 (Grade II)[notes 2]
  • Moderate dysplasia confined to the basal 2/3 of the epithelium
CIN 3 (Grade III)[notes 3]
  • Severe dysplasia with undifferentiated neoplastic cells that span more than 2/3 of the epithelium
  • May involve the full thickness
  • May also be referred to as cervical carcinoma in situ
File:Histopathology of CIN 3.jpg

Notes

  1. HSIL+ encompasses HSIL, AGC, and cancer
  2. CIN 2+ encompasses CIN 2, CIN 3, adenocarcinoma in situ (AIS), and cancer
  3. CIN 3+ encompasses CIN 3, AIS, and cancer


Main page

References

  1. Source image by Ed Uthman from Houston, TX, USA. Creative Commons Attribution 2.0 Generic (CC BY 2.0) license
  2. Nagi, Chandandeep S.; Schlosshauer, Peter W. (2006). "Endocervical glandular involvement is associated with high-grade SIL ". Gynecologic Oncology 102 (2): 240–243. doi:10.1016/j.ygyno.2005.12.029. ISSN 00908258. 

Image sources