Template:Mitotic count in invasive breast cancer: Difference between revisions
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}}</noinclude>[[File:Mitosis appearances in breast cancer.jpg|thumb|Mitosis appearances in breast cancer]] | }}</noinclude>[[File:Mitosis appearances in breast cancer.jpg|thumb|Mitosis appearances in breast cancer]] | ||
{{edit|Template:Mitotic count in invasive cancer}}<br> | {{edit|Template:Mitotic count in invasive breast cancer}}<br> | ||
Mitotic figures are counted only at the periphery of the tumor, and counting should begin in the most mitotically active areas, and in at least 10 high-power fields (HPFs). If you know that the area of your high power field is about 0.2mm<sup>2</sup>, then you may score mitotic count as follows:<ref name=cap-invasive>{{cite web|url=https://documents.cap.org/protocols/Breast.Invasive_4.7.0.1.REL_CAPCP.pdf|Protocol for the Examination of Resection Specimens from Patients with Invasive Carcinoma of the Breast Version: 4.7.0.1 - Table 1. Score Categories According to Field Diameter and Mitotic Count|website=College of American Pathologists}} Protocol Posting Date: September 2022</ref> | Mitotic figures are counted only at the periphery of the tumor, and counting should begin in the most mitotically active areas, and in at least 10 high-power fields (HPFs). If you know that the area of your high power field is about 0.2mm<sup>2</sup>, then you may score mitotic count as follows:<ref name=cap-invasive>{{cite web|url=https://documents.cap.org/protocols/Breast.Invasive_4.7.0.1.REL_CAPCP.pdf|Protocol for the Examination of Resection Specimens from Patients with Invasive Carcinoma of the Breast Version: 4.7.0.1 - Table 1. Score Categories According to Field Diameter and Mitotic Count|website=College of American Pathologists}} Protocol Posting Date: September 2022</ref> | ||
*'''1 point''': ≤7 mitoses per 10 HPFs | *'''1 point''': ≤7 mitoses per 10 HPFs | ||
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*'''3 points''': ≥15 mitoses per 10 HPFs | *'''3 points''': ≥15 mitoses per 10 HPFs | ||
If you have a significant different HPF area or you are not sure, count 10 HPFs and calculate the number of mitoses per mm<sup>2</sup> ({{further|Evaluation#Counts per mm2}}): | If you have a significant different HPF area or you are not sure, count 10 HPFs and calculate the number of mitoses per mm<sup>2</sup> ({{further|Evaluation#Counts per mm2}}): | ||
*'''1 point''': ≤3 mitoses per | *'''1 point''': ≤3 mitoses per mm<sup>2</sup> | ||
*'''2 points''': 4 to 7 mitoses per | *'''2 points''': 4 to 7 mitoses per mm<sup>2</sup> | ||
*'''3 points''': ≥7 mitoses per | *'''3 points''': ≥7 mitoses per mm<sup>2</sup> | ||
A table of counts for various HPF sizes is available at the College of American Pathologists. [https://documents.cap.org/protocols/Breast.Invasive_4.7.0.1.REL_CAPCP.pdf]<noinclude> | A table of counts for various HPF sizes is available at the College of American Pathologists. [https://documents.cap.org/protocols/Breast.Invasive_4.7.0.1.REL_CAPCP.pdf]<noinclude> | ||
{{Bottom}} | {{Bottom}} | ||
</noinclude> | </noinclude> | ||
Revision as of 18:58, 6 November 2022
Author:
Mitotic figures are counted only at the periphery of the tumor, and counting should begin in the most mitotically active areas, and in at least 10 high-power fields (HPFs). If you know that the area of your high power field is about 0.2mm2, then you may score mitotic count as follows:[1]
- 1 point: ≤7 mitoses per 10 HPFs
- 2 points: 8 to 14 mitoses per 10 HPFs
- 3 points: ≥15 mitoses per 10 HPFs
If you have a significant different HPF area or you are not sure, count 10 HPFs and calculate the number of mitoses per mm2 (Further information: Evaluation#Counts per mm2 ):
- 1 point: ≤3 mitoses per mm2
- 2 points: 4 to 7 mitoses per mm2
- 3 points: ≥7 mitoses per mm2
A table of counts for various HPF sizes is available at the College of American Pathologists. [1]
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
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References
- ↑ Error on call to Template:cite web: Parameters url and title must be specified. . College of American Pathologists. Protocol Posting Date: September 2022
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