Lichen sclerosus: Difference between revisions

From patholines.org
Jump to navigation Jump to search
Mikael Häggström (talk | contribs)
Mikael Häggström (talk | contribs)
Line 13: Line 13:
==Microscopic evaluation==
==Microscopic evaluation==
[[File:Micrograph of lichen sclerosus.jpg|thumb|Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, initial homogenization of collagen in the dermis.<ref>{{cite journal|last1=Jędrowiak|first1=Anna|last2=Kobusiewicz|first2=Aleksandra|last3=Trznadel-Grodzka|first3=Ewa|last4=Kaszuba|first4=Andrzej|title=Dermoscopic findings in extragenital lichen sclerosus|journal=Our Dermatology Online|volume=9|issue=2|year=2018|pages=197–199|issn=20819390|doi=10.7241/ourd.20182.24}}<br>- "Figures - available via license: CC BY 4.0"</ref>]]
[[File:Micrograph of lichen sclerosus.jpg|thumb|Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, initial homogenization of collagen in the dermis.<ref>{{cite journal|last1=Jędrowiak|first1=Anna|last2=Kobusiewicz|first2=Aleksandra|last3=Trznadel-Grodzka|first3=Ewa|last4=Kaszuba|first4=Andrzej|title=Dermoscopic findings in extragenital lichen sclerosus|journal=Our Dermatology Online|volume=9|issue=2|year=2018|pages=197–199|issn=20819390|doi=10.7241/ourd.20182.24}}<br>- "Figures - available via license: CC BY 4.0"</ref>]]
Findings associated with lichen sclerosus are:<ref name="emed">{{cite web|url=https://emedicine.medscape.com/article/1123316-overview#|title=Lichen Sclerosus|website=EMedicine|author=Lisa K Pappas-Taffer}} Updated: May 17, 2018</ref> The biopsies are also checked for signs of [[dysplasia]].<ref name="Shelley2006">{{Cite journal | last1 = Shelley | first1 = W. B. | last2 = Shelley | first2 = E. D. | last3 = Amurao | first3 = C. V. | doi = 10.1111/j.1365-4632.2006.02978.x | title = Treatment of lichen sclerosus with antibiotics | journal = International Journal of Dermatology | volume = 45 | issue = 9 | pages = 1104–1106 | year = 2006 | pmid =  16961523| pmc = }}</ref>
Findings associated with lichen sclerosus are:<ref name="emed">{{cite web|url=https://emedicine.medscape.com/article/1123316-overview#|title=Lichen Sclerosus|website=EMedicine|author=Lisa K Pappas-Taffer}} Updated: May 17, 2018</ref>
*Hyperkeratosis
*Hyperkeratosis
*Atrophic epidermis
*Atrophic epidermis
*Sclerosis]] of the dermis
*Sclerosis]] of the dermis
*Lymphocytes in the dermis
*Lymphocytes in the dermis
Also look for dysplasia.<ref name="Shelley2006">{{Cite journal | last1 = Shelley | first1 = W. B. | last2 = Shelley | first2 = E. D. | last3 = Amurao | first3 = C. V. | doi = 10.1111/j.1365-4632.2006.02978.x | title = Treatment of lichen sclerosus with antibiotics | journal = International Journal of Dermatology | volume = 45 | issue = 9 | pages = 1104–1106 | year = 2006 | pmid =  16961523| pmc = }}</ref>


==Reporting==
==Reporting==
{{Reporting}}
{{Reporting}}
{{Bottom}}
{{Bottom}}

Revision as of 11:31, 20 January 2020

Author: Mikael Häggström [note 1]

Presentations

Mainly including:

Fixation

Generally 10% neutral buffered formalin.

  See also: General notes on fixation


Gross processing

  See also: General notes on gross processing


Microscopic evaluation

File:Micrograph of lichen sclerosus.jpg
Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, initial homogenization of collagen in the dermis.[1]

Findings associated with lichen sclerosus are:[2]

  • Hyperkeratosis
  • Atrophic epidermis
  • Sclerosis]] of the dermis
  • Lymphocytes in the dermis

Also look for dysplasia.[3]

Reporting

  See also: General notes on reporting


Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Jędrowiak, Anna; Kobusiewicz, Aleksandra; Trznadel-Grodzka, Ewa; Kaszuba, Andrzej (2018). "Dermoscopic findings in extragenital lichen sclerosus ". Our Dermatology Online 9 (2): 197–199. doi:10.7241/ourd.20182.24. ISSN 20819390. 
    - "Figures - available via license: CC BY 4.0"
  2. Lisa K Pappas-Taffer. Lichen Sclerosus. EMedicine. Updated: May 17, 2018
  3. Shelley, W. B.; Shelley, E. D.; Amurao, C. V. (2006). "Treatment of lichen sclerosus with antibiotics ". International Journal of Dermatology 45 (9): 1104–1106. doi:10.1111/j.1365-4632.2006.02978.x. PMID 16961523. 

Image sources