Verrucous oral lesions: Difference between revisions
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==Microscopic evaluation== | ==Microscopic evaluation== | ||
Look for signs of koilocyte-like changes, which may indicate verrucous squamous cell carcinoma, and which typically only has low atypia | Look for signs of koilocyte-like changes, which may indicate verrucous squamous cell carcinoma, and which typically only has low atypia:<ref name="PaolinoDonati2017">Initially copied from: {{cite journal|last1=Paolino|first1=Giovanni|last2=Donati|first2=Michele|last3=Didona|first3=Dario|last4=Mercuri|first4=Santo|last5=Cantisani|first5=Carmen|title=Histology of Non-Melanoma Skin Cancers: An Update|journal=Biomedicines|volume=5|issue=4|year=2017|pages=71|issn=2227-9059|doi=10.3390/biomedicines5040071}} - "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)."</ref> | ||
<gallery mode=packed heights=190> | <gallery mode=packed heights=190> | ||
File:Micrograph of penile verrucous carcinoma - 20x.jpg | File:Micrograph of penile verrucous carcinoma - 20x.jpg | ||
Revision as of 11:32, 4 March 2020
Author:
Mikael Häggström [note 1]
Verrucous oral lesions have hypergranulosis and/or hyperkeratosis as the most conspicuous finding.
Microscopic evaluation
Look for signs of koilocyte-like changes, which may indicate verrucous squamous cell carcinoma, and which typically only has low atypia:[1]
Verrucous squamous cell carcinoma (images are from penis).
If uncertain, perform immunohistochemistry for Ki67 and p53.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Initially copied from: Paolino, Giovanni; Donati, Michele; Didona, Dario; Mercuri, Santo; Cantisani, Carmen (2017). "Histology of Non-Melanoma Skin Cancers: An Update ". Biomedicines 5 (4): 71. doi:. ISSN 2227-9059. - "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)."
Image sources