Gallbladder: Difference between revisions
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[[File:Gross pathology of gallbladder carcinoma.jpg|thumb|Gross pathology of gallbladder carcinoma, with a prominent nodule.]] | [[File:Gross pathology of gallbladder carcinoma.jpg|thumb|Gross pathology of gallbladder carcinoma, with a prominent nodule.]] | ||
May be done by a distal-to-proximal approach: Identify the ''ampulla of Vater'', possibly by bile flow when squeezing the gallbladder. Dissect the common bile duct, cystic duct and thereafter the gallbladder. Look mainly for signs of carcinoma. | May be done by a distal-to-proximal approach: Identify the ''ampulla of Vater'', possibly by bile flow when squeezing the gallbladder. Dissect the common bile duct, cystic duct and thereafter the gallbladder. Look mainly for signs of carcinoma. | ||
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File:Gross pathology of cholesterolosis.jpg|thumb|Cholesterolosis (yellow streaks of cholesterol deposition) is a frequent incidental finding.<ref>{{cite journal|last1=Talwar|first1=OP|last2=K.C.|first2=Geetika|title=Histomorphological changes in gall bladder diseases and its association with helicobacter infection|journal=Journal of Pathology of Nepal|volume=4|issue=8|year=2014|pages=617–622|issn=2091-0908|doi=10.3126/jpn.v4i8.11607}}<br>- "Figures - available via license: CC BY 4.0"</ref> | |||
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{{Further|Autopsy}} | {{Further|Autopsy}} | ||
{{Fixation - standard}} | {{Fixation - standard}} | ||
{{Fixation - general notes}} | {{Fixation - general notes}} | ||
==Microscopic evaluation== | ==Microscopic evaluation== | ||
Look at least at the epithelial lining, for atypia. | Look at least at the epithelial lining, for atypia. | ||
Revision as of 11:17, 19 March 2020
Author:
Mikael Häggström [note 1]
Common requests
Basic autopsy cutting
May be done by a distal-to-proximal approach: Identify the ampulla of Vater, possibly by bile flow when squeezing the gallbladder. Dissect the common bile duct, cystic duct and thereafter the gallbladder. Look mainly for signs of carcinoma.
-
Cholesterolosis (yellow streaks of cholesterol deposition) is a frequent incidental finding.[1]
![Cholesterolosis (yellow streaks of cholesterol deposition) is a frequent incidental finding.[1]](/index.php?title=Special:Upload&wpDestFile=Gross_pathology_of_cholesterolosis.jpg){kind=link}
Further information: Autopsy
Fixation
Generally 10% neutral buffered formalin.
See also: General notes on fixation
Microscopic evaluation
Look at least at the epithelial lining, for atypia.
-
Histopathology of gallbladder carcinoma, with marked nuclear pleomorphism
Common findings
Report if incidentally discovered:
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Substantial amount of foam cells within lamina propria, conferring a diagnosis of cholesterolosis.
Report
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
Image sources