Arteries: Difference between revisions
Jump to navigation
Jump to search
Started |
+Aneurysm |
||
| Line 3: | Line 3: | ||
|author2= | |author2= | ||
}} | }} | ||
==Presentations== | |||
*[[Aneurysm]] | |||
==Gross processing== | ==Gross processing== | ||
A minimal gross processing of arteries includes a longitudinal dissection and inspection of tunica intima. | A minimal gross processing of arteries includes a longitudinal dissection and inspection of tunica intima. | ||
| Line 13: | Line 17: | ||
*Estimate the maximum percentage of stenosis for each artery. Cross-sections collapse more or less after cutting, and estimations should be made as if the walls again took a circular shape. | *Estimate the maximum percentage of stenosis for each artery. Cross-sections collapse more or less after cutting, and estimations should be made as if the walls again took a circular shape. | ||
<gallery mode=packed heights= | <gallery mode=packed heights=250> | ||
File:Histopathology of pre-atherosclerotic intimal lesions.jpg|Histopathology of '''pre-atherosclerotic intimal lesions''': Intimal thickening (A) consists mainly of smooth muscle cells in a proteoglycan-rich matrix. Intimal xanthoma (B) displays intimal thickening with isolated foam cells (arrows).<ref name="YangFisher2017">{{cite journal|last1=Yang|first1=Wen Jie|last2=Fisher|first2=Mark|last3=Zheng|first3=Lu|last4=Niu|first4=Chun Bo|last5=Paganini-Hill|first5=Annlia|last6=Zhao|first6=Hai Lu|last7=Xu|first7=Yun|last8=Wong|first8=Ka Sing|last9=Ng|first9=Ho Keung|last10=Chen|first10=Xiang Yan|title=Histological Characteristics of Intracranial Atherosclerosis in a Chinese Population: A Postmortem Study|journal=Frontiers in Neurology|volume=8|year=2017|issn=1664-2295|doi=10.3389/fneur.2017.00488}}</ref> | File:Histopathology of pre-atherosclerotic intimal lesions.jpg|Histopathology of '''pre-atherosclerotic intimal lesions''': Intimal thickening (A) consists mainly of smooth muscle cells in a proteoglycan-rich matrix. Intimal xanthoma (B) displays intimal thickening with isolated foam cells (arrows).<ref name="YangFisher2017">{{cite journal|last1=Yang|first1=Wen Jie|last2=Fisher|first2=Mark|last3=Zheng|first3=Lu|last4=Niu|first4=Chun Bo|last5=Paganini-Hill|first5=Annlia|last6=Zhao|first6=Hai Lu|last7=Xu|first7=Yun|last8=Wong|first8=Ka Sing|last9=Ng|first9=Ho Keung|last10=Chen|first10=Xiang Yan|title=Histological Characteristics of Intracranial Atherosclerosis in a Chinese Population: A Postmortem Study|journal=Frontiers in Neurology|volume=8|year=2017|issn=1664-2295|doi=10.3389/fneur.2017.00488}}</ref> | ||
File:Histopathology of progressive atherosclerotic lesions.jpg|Histopathology of '''progressive atherosclerotic lesions''': Pathological intima thickening (A) has some extracellular lipid (EL) present deep in the lesion without true necrosis. Fibrous cap atheroma (B) has a well-formed necrotic core (NC) containing lipids with an overlying thick fibrous cap (FC). Fibrocalcific plaques (C) are heavily calcified lesions with or without a necrotic core.<ref name="YangFisher2017"/> | File:Histopathology of progressive atherosclerotic lesions.jpg|Histopathology of '''progressive atherosclerotic lesions''': Pathological intima thickening (A) has some extracellular lipid (EL) present deep in the lesion without true necrosis. Fibrous cap atheroma (B) has a well-formed necrotic core (NC) containing lipids with an overlying thick fibrous cap (FC). Fibrocalcific plaques (C) are heavily calcified lesions with or without a necrotic core.<ref name="YangFisher2017"/> | ||
Revision as of 08:42, 19 August 2020
Author:
Mikael Häggström [note 1]
Presentations
Gross processing
A minimal gross processing of arteries includes a longitudinal dissection and inspection of tunica intima.
Consecutive cross-sections allows for a detection and estimation of atherosclerotic stenosis.
Microscopic examination
- Look for atherosclerosis and thrombosis.
- Estimate the maximum percentage of stenosis for each artery. Cross-sections collapse more or less after cutting, and estimations should be made as if the walls again took a circular shape.
-
Histopathology of pre-atherosclerotic intimal lesions: Intimal thickening (A) consists mainly of smooth muscle cells in a proteoglycan-rich matrix. Intimal xanthoma (B) displays intimal thickening with isolated foam cells (arrows).[1]
-
Histopathology of progressive atherosclerotic lesions: Pathological intima thickening (A) has some extracellular lipid (EL) present deep in the lesion without true necrosis. Fibrous cap atheroma (B) has a well-formed necrotic core (NC) containing lipids with an overlying thick fibrous cap (FC). Fibrocalcific plaques (C) are heavily calcified lesions with or without a necrotic core.[1]
-
Histopathology of plaque components in atherosclerosis: (A) Intraplaque neovasculature (arrows); (B) intraplaque hemorrhage; (C) large areas of calcification seen as purple morula; (D) lumen thrombus (arrowhead); stained with hematoxylin and eosin (H&E); (E) macrophage infiltration; stained with CD68 antibodies.[1]
![Histopathology of pre-atherosclerotic intimal lesions: Intimal thickening (A) consists mainly of smooth muscle cells in a proteoglycan-rich matrix. Intimal xanthoma (B) displays intimal thickening with isolated foam cells (arrows).[1]](/index.php?title=Special:Upload&wpDestFile=Histopathology_of_pre-atherosclerotic_intimal_lesions.jpg){kind=link}
![Histopathology of progressive atherosclerotic lesions: Pathological intima thickening (A) has some extracellular lipid (EL) present deep in the lesion without true necrosis. Fibrous cap atheroma (B) has a well-formed necrotic core (NC) containing lipids with an overlying thick fibrous cap (FC). Fibrocalcific plaques (C) are heavily calcified lesions with or without a necrotic core.[1]](/index.php?title=Special:Upload&wpDestFile=Histopathology_of_progressive_atherosclerotic_lesions.jpg){kind=link}
![Histopathology of plaque components in atherosclerosis: (A) Intraplaque neovasculature (arrows); (B) intraplaque hemorrhage; (C) large areas of calcification seen as purple morula; (D) lumen thrombus (arrowhead); stained with hematoxylin and eosin (H&E); (E) macrophage infiltration; stained with CD68 antibodies.[1]](/index.php?title=Special:Upload&wpDestFile=Histopathology_of_plaque_components_in_atherosclerosis.jpg){kind=link}
Microscopy report
- Maximum percentage of stenosis for each artery.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 1.2 Yang, Wen Jie; Fisher, Mark; Zheng, Lu; Niu, Chun Bo; Paganini-Hill, Annlia; Zhao, Hai Lu; Xu, Yun; Wong, Ka Sing; et al. (2017). "Histological Characteristics of Intracranial Atherosclerosis in a Chinese Population: A Postmortem Study ". Frontiers in Neurology 8. doi:. ISSN 1664-2295.
Image sources