Template:Esophagitis: Difference between revisions

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Mikael Häggström (talk | contribs)
Mikael Häggström (talk | contribs)
m Esophagitis: Loss of orientation
 
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*'''Basal cell hyperplasia''' exceeding 15 - 20% of the epithelial thickness.
*'''Basal cell hyperplasia''' exceeding 15 - 20% of the epithelial thickness.
*'''Stromal papillae''' reaching upper third of the epithelium.
*'''Stromal papillae''' reaching upper third of the epithelium.
*'''Loss of orientation''' of superficial epithelial cells.
*'''Ballooned squamous cells'''
*'''Ballooned squamous cells'''
<gallery>
<gallery>
File:Histology of an eosinophil in esophageal epithelium.jpg|thumb|180px|An intra-epithelial '''eosinophil''' (characterized by its bilobed nucleus despite scant visible eosinophilic cytoplasm)
File:Histology of an eosinophil in esophageal epithelium.jpg|thumb|180px|An intra-epithelial '''eosinophil''' (characterized by its bilobed nucleus despite scant visible eosinophilic cytoplasm)
</gallery>
</gallery>

Latest revision as of 15:44, 10 December 2020

Esophagitis

GE junction with chronic esophagitis, including plasma cells (black arrow), an acute inflammation with neutrophils (white arrow), as well as basal layer hyperplasia (yellow double-headed arrow).

Look for signs of (reflux) esophagitis, mainly:[1]

  • Inflammatory cells, especially when intra-epithelial. Neutrophils confer a diagnosis of acute inflammation, while plasma cells, eosinophils and excess T cells confer a diagnosis of chronic inflammation. In eosinophil-predominant inflammation, also evaluate as suspected eosinophilic esophagitis.
  • Basal cell hyperplasia exceeding 15 - 20% of the epithelial thickness.
  • Stromal papillae reaching upper third of the epithelium.
  • Loss of orientation of superficial epithelial cells.
  • Ballooned squamous cells
  1. Elliot Weisenberg. Esophagus - Esophagitis - Reflux esophagitis / gastroesophageal reflux disease. Pathology Outlines. Topic Completed: 1 October 2012. Minor changes: 8 July 2020