Pigmented macrophages of the lung: Difference between revisions
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When seeing pigmented macrophages of the lung, | When seeing pigmented macrophages of the lung, categorize as follows: | ||
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File:Histopathology of anthracotic macrophage in lung, annotated.jpg| | {|class=wikitable | ||
File:Histopathology of | ! Disease !! Macrophages !! Pigment appearance (HE stain) !! Associated medical history !! Image !! Image comment | ||
</ | |- | ||
! Anthracosis | |||
| || Black-brown | |||
| | |||
*Age and urban dwelling.<ref name="robspath">{{cite book | title=Robbins Pathologic Basis of Disease| last=Cotran|author2=Kumar, Collins| publisher=W.B Saunders Company| location=Philadelphia| isbn=978-0-7216-7335-6| year=1999}}</ref> | |||
*Coal workers<ref>{{cite journal |author=Morgan WK |title=Industrial bronchitis |journal=Br J Ind Med |volume=35 |issue=4 |pages=285–91 |date=November 1978 |pmid=367424 |pmc=1008445 }}</ref> | |||
| [[File:Histopathology of anthracotic macrophage in lung, annotated.jpg|200px]] | |||
| Black arrow shows interstitial anthracotic pigment. Nearby macrophages (white arrow) can be presumed to contain anthracotic pigment. Reporting is optional in mild cases in the elderly. | |||
|- | |||
! Respiratory bronchiolitis | |||
| "Smoker's macrophages" | |||
| Yellow to light brown and finely granular<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/lungnontumorrespbronchiolitis.html|title=Lung - Other interstitial pneumonitis / fibrosis - Respiratory bronchiolitis|author=William Perry, M.D., M.P.H., Kristine Konopka, M.D.}} Topic Completed: 1 July 2020. Minor changes: 1 July 2020.</ref> || Tobacco smoking | |||
| [[File:Histopathology of respiratory bronchiolitis.jpg|200px]] | |||
| Smoker's macrophages (arrow); mild interstitial lymphocytic infiltrate and mild fibrosis (arrowhead)<ref>{{cite journal|last1=Sousa|first1=Célia|last2=Rodrigues|first2=Márcio|last3=Carvalho|first3=André|last4=Viamonte|first4=Bárbara|last5=Cunha|first5=Rui|last6=Guimarães|first6=Susana|last7=de Moura|first7=Conceição Souto|last8=Morais|first8=António|last9=Pereira|first9=José Miguel|title=Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation|journal=Insights into Imaging|volume=10|issue=1|year=2019|issn=1869-4101|doi=10.1186/s13244-019-0765-z}}<br>- This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)</ref> | |||
|- | |||
! '''Heart failure''' | |||
| Siderophages || Brown granules<ref>{{cite web|url=https://webpath.med.utah.edu/LUNGHTML/LUNG101.html|title=Pulmonary congestion|website=The Internet Pathology Laboratory for Medical Education, Hosted By The University of Utah Eccles Health Sciences Library|author=Edward C. Klatt|accessddate=2021-02-16}}</ref> | |||
*Heart failure | |||
*Pulmonary hemorrhage | |||
| [[File:Histopathology of pulmonary congestion and siderophages.jpg|200px]] | |||
|} | |||
{{Bottom}} | {{Bottom}} | ||
Revision as of 17:37, 16 February 2021
Author:
Mikael Häggström [note 1]
When seeing pigmented macrophages of the lung, categorize as follows:
| Disease | Macrophages | Pigment appearance (HE stain) | Associated medical history | Image | Image comment |
|---|---|---|---|---|---|
| Anthracosis | Black-brown | File:Histopathology of anthracotic macrophage in lung, annotated.jpg | Black arrow shows interstitial anthracotic pigment. Nearby macrophages (white arrow) can be presumed to contain anthracotic pigment. Reporting is optional in mild cases in the elderly. | ||
| Respiratory bronchiolitis | "Smoker's macrophages" | Yellow to light brown and finely granular[3] | Tobacco smoking | File:Histopathology of respiratory bronchiolitis.jpg | Smoker's macrophages (arrow); mild interstitial lymphocytic infiltrate and mild fibrosis (arrowhead)[4] |
| Heart failure | Siderophages | Brown granules[5]
|
File:Histopathology of pulmonary congestion and siderophages.jpg |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Cotran; Kumar, Collins (1999). Robbins Pathologic Basis of Disease . Philadelphia: W.B Saunders Company. ISBN 978-0-7216-7335-6.
- ↑ Morgan WK (November 1978). "Industrial bronchitis ". Br J Ind Med 35 (4): 285–91. PMID 367424.
- ↑ William Perry, M.D., M.P.H., Kristine Konopka, M.D.. Lung - Other interstitial pneumonitis / fibrosis - Respiratory bronchiolitis. Topic Completed: 1 July 2020. Minor changes: 1 July 2020.
- ↑ Sousa, Célia; Rodrigues, Márcio; Carvalho, André; Viamonte, Bárbara; Cunha, Rui; Guimarães, Susana; de Moura, Conceição Souto; Morais, António; et al. (2019). "Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation
". Insights into Imaging 10 (1). doi:. ISSN 1869-4101.
- This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) - ↑ Edward C. Klatt. Pulmonary congestion. The Internet Pathology Laboratory for Medical Education, Hosted By The University of Utah Eccles Health Sciences Library.
Image sources