Smooth muscle tumor: Difference between revisions
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[[File:Leiomyoma.jpg|thumb|Smooth muscle tumor (in this case leiomyoma).]] | [[File:Leiomyoma.jpg|thumb|Smooth muscle tumor (in this case leiomyoma).]] | ||
{{Comprehensiveness}} | |||
==Gross processing== | ==Gross processing== | ||
===Gross examination=== | ===Gross examination=== | ||
[[File:Fibroid locations.jpg|thumb|Fibroid locations.]] | |||
Examine and describe:<ref name=stora>{{Stora utskärningen}}</ref> | Examine and describe:<ref name=stora>{{Stora utskärningen}}</ref> | ||
*Location | *Location. If in the uterus: | ||
:*Intramural/submucosal/subserosal (see image) | |||
:*{{Moderate-begin}}Posterior/anterior/right or left lateral.{{Moderate-end}} | |||
*Number of tumors, if multiple | *Number of tumors, if multiple | ||
*Size | *Size | ||
*Demarcation | *{{Moderate-begin}}Presence or absence of any hemorrhage or necrosis.{{Moderate-end}} | ||
*{{Comprehensive-begin}}Demarcation{{Comprehensive-end}} | |||
===Selection=== | ===Selection=== | ||
Revision as of 11:07, 8 April 2021
Author:
Mikael Häggström [note 1]
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Gross processing
Gross examination
Examine and describe:[1]
- Location. If in the uterus:
- Intramural/submucosal/subserosal (see image)
- (Posterior/anterior/right or left lateral.)
- Number of tumors, if multiple
- Size
- (Presence or absence of any hemorrhage or necrosis.)
- ((Demarcation))
Selection
In case of hysterectomy, submit pieces from all smooth muscle tumors >5 cm in diameter.[1]
Submit any macroscopically abnormal parts of the tumors (hemorrhagic, necrotic, brittle or softening areas, and areas with blurry delimitation).[1]
Microscopic examination
Distinguish leiomyoma (benign) from leiomyosarcoma (malignant).
-
Leiomyomas typically show smooth muscle in a whorled (fascicular) pattern[2]
-
Leiomyoma, with areas where the cellularity is relatively lower (left) and higher (right).
-
Epithelioid leiomyoma
-
Leiomyoma with palisading pattern
-
Leiomyosarcoma: Variable atypia, often with cytoplasmic vacuoles at both ends of nuclei, and frequent mitoses.[3]
-
Epithelioid leiomyosarcoma
![Leiomyomas typically show smooth muscle in a whorled (fascicular) pattern[2]](/index.php?title=Special:Upload&wpDestFile=Histopathology_of_uterine_leiomyoma.jpg){kind=link}
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.jpg){kind=link}
![Leiomyosarcoma: Variable atypia, often with cytoplasmic vacuoles at both ends of nuclei, and frequent mitoses.[3]](/index.php?title=Special:Upload&wpDestFile=Histopathology_of_leiomyosarcoma.jpg){kind=link}
Further information: Evaluation of tumors
Microscopic report
Report:
- Microscopic findings, including any visible linings
- Diagnosis or most probable one
- Any linings or borders.
Example, for a cervical polyp:
|
Polyp lined by a single layer of columnar epithelium consistent with endometrium. The interior consists of smooth muscles in a whorled pattern. No atypia. The finding is consistent with a pedunculated submucosal leiomyoma. |
See also: General notes on reporting
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 1.2 Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg. Stora utskärningen. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-26.
- ↑ Mohamed Mokhtar Desouki. Uterus - Stromal tumors - Leiomyoma. pathology Outlines. Topic Completed: 1 August 2011. Revised: 15 December 2019
- ↑ Vijay Shankar, M.D.. Soft tissue - Smooth muscle - Leiomyosarcoma - general. Pathology Outlines. Topic Completed: 1 November 2012. Revised: 11 September 2019
Image sources