Ductal carcinoma in situ: Difference between revisions
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Malignant epithelial cells confined to the ductal system of the breast.<ref name="Siziopikou2013">{{cite journal|last1=Siziopikou|first1=Kalliopi P.|title=Ductal Carcinoma In Situ of the Breast: Current Concepts and Future Directions|journal=Archives of Pathology & Laboratory Medicine|volume=137|issue=4|year=2013|pages=462–466|issn=0003-9985|doi=10.5858/arpa.2012-0078-RA}}</ref> | Malignant epithelial cells confined to the ductal system of the breast.<ref name="Siziopikou2013">{{cite journal|last1=Siziopikou|first1=Kalliopi P.|title=Ductal Carcinoma In Situ of the Breast: Current Concepts and Future Directions|journal=Archives of Pathology & Laboratory Medicine|volume=137|issue=4|year=2013|pages=462–466|issn=0003-9985|doi=10.5858/arpa.2012-0078-RA}}</ref> | ||
===Differential diagnoses== | ===Differential diagnoses=== | ||
;[[Invasive ductal carcinoma]]: Has invasion through the basement membrane.<ref name="Siziopikou2013"/> | ;[[Invasive ductal carcinoma]]: Has invasion through the basement membrane.<ref name="Siziopikou2013"/> | ||
Revision as of 07:54, 2 October 2019
Author:
Mikael Häggström [note 1]
Gross examination
As per:
or mastectomy.
Microscopic evaluation
Malignant epithelial cells confined to the ductal system of the breast.[1]
Differential diagnoses
- Invasive ductal carcinoma
- Has invasion through the basement membrane.[1]
- Atypical ductal hyperplasia
There is no single definite cutoff, but the following are suggested cutoffs defining a ductal carcinoma in situ:[2]
- Size over 2 mm.
- Involving more than one duct.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Siziopikou, Kalliopi P. (2013). "Ductal Carcinoma In Situ of the Breast: Current Concepts and Future Directions ". Archives of Pathology & Laboratory Medicine 137 (4): 462–466. doi:. ISSN 0003-9985.
- ↑ Tozbikian, Gary; Brogi, Edi; Vallejo, Christina E.; Giri, Dilip; Murray, Melissa; Catalano, Jeffrey; Olcese, Cristina; Van Zee, Kimberly J.; et al. (2016). "Atypical Ductal Hyperplasia Bordering on Ductal Carcinoma In Situ ". International Journal of Surgical Pathology 25 (2): 100–107. doi:. ISSN 1066-8969.
Image sources