Ductal carcinoma in situ: Difference between revisions

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;[[Invasive ductal carcinoma]]: Has invasion through the basement membrane.<ref name="Siziopikou2013"/>
;[[Invasive ductal carcinoma]]: Has invasion through the basement membrane.<ref name="Siziopikou2013"/>


;Atypical ductal hyperplasia
;[[Atypical ductal hyperplasia]]
There is no single definite cutoff, but the following are suggested cutoffs defining a ductal carcinoma in situ:<ref name="TozbikianBrogi2016">{{cite journal|last1=Tozbikian|first1=Gary|last2=Brogi|first2=Edi|last3=Vallejo|first3=Christina E.|last4=Giri|first4=Dilip|last5=Murray|first5=Melissa|last6=Catalano|first6=Jeffrey|last7=Olcese|first7=Cristina|last8=Van Zee|first8=Kimberly J.|last9=Wen|first9=Hannah Yong|title=Atypical Ductal Hyperplasia Bordering on Ductal Carcinoma In Situ|journal=International Journal of Surgical Pathology|volume=25|issue=2|year=2016|pages=100–107|issn=1066-8969|doi=10.1177/1066896916662154}}</ref>
There is no single definite cutoff, but the following are suggested cutoffs defining a ductal carcinoma in situ:<ref name="TozbikianBrogi2016">{{cite journal|last1=Tozbikian|first1=Gary|last2=Brogi|first2=Edi|last3=Vallejo|first3=Christina E.|last4=Giri|first4=Dilip|last5=Murray|first5=Melissa|last6=Catalano|first6=Jeffrey|last7=Olcese|first7=Cristina|last8=Van Zee|first8=Kimberly J.|last9=Wen|first9=Hannah Yong|title=Atypical Ductal Hyperplasia Bordering on Ductal Carcinoma In Situ|journal=International Journal of Surgical Pathology|volume=25|issue=2|year=2016|pages=100–107|issn=1066-8969|doi=10.1177/1066896916662154}}</ref>
*Size over 2 mm.
*Size over 2 mm.
*Involving more than one duct.
*Involving more than one duct.
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Revision as of 08:00, 2 October 2019

Author: Mikael Häggström [note 1]

Gross examination

As per:

or mastectomy.

Microscopic evaluation

File:DCIS - Intraductal carcinoma of the breast.jpg

Malignant epithelial cells confined to the ductal system of the breast.[1]

Differential diagnoses

Invasive ductal carcinoma
Has invasion through the basement membrane.[1]
Atypical ductal hyperplasia

There is no single definite cutoff, but the following are suggested cutoffs defining a ductal carcinoma in situ:[2]

  • Size over 2 mm.
  • Involving more than one duct.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 Siziopikou, Kalliopi P. (2013). "Ductal Carcinoma In Situ of the Breast: Current Concepts and Future Directions ". Archives of Pathology & Laboratory Medicine 137 (4): 462–466. doi:10.5858/arpa.2012-0078-RA. ISSN 0003-9985. 
  2. Tozbikian, Gary; Brogi, Edi; Vallejo, Christina E.; Giri, Dilip; Murray, Melissa; Catalano, Jeffrey; Olcese, Cristina; Van Zee, Kimberly J.; et al. (2016). "Atypical Ductal Hyperplasia Bordering on Ductal Carcinoma In Situ ". International Journal of Surgical Pathology 25 (2): 100–107. doi:10.1177/1066896916662154. ISSN 1066-8969. 

Image sources