Template:Cervical dysplasia: Difference between revisions

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[[File:Histopathology of CIN 3 with endocervical gland invasion.jpg|thumb|center|200px|Endocervical gland invasion is associated with high-grade lesions.<ref name="NagiSchlosshauer2006">{{cite journal|last1=Nagi|first1=Chandandeep S.|last2=Schlosshauer|first2=Peter W.|title=Endocervical glandular involvement is associated with high-grade SIL|journal=Gynecologic Oncology|volume=102|issue=2|year=2006|pages=240–243|issn=00908258|doi=10.1016/j.ygyno.2005.12.029}}</ref>]]
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File:Spectrum of SIL cervical dysplasia.png|Spectrum from normal to high grade SIL
File:Histopathology of CIN 3 with endocervical gland invasion.jpg|'''Endocervical gland invasion''' is associated with high-grade lesions.<ref name="NagiSchlosshauer2006">{{cite journal|last1=Nagi|first1=Chandandeep S.|last2=Schlosshauer|first2=Peter W.|title=Endocervical glandular involvement is associated with high-grade SIL|journal=Gynecologic Oncology|volume=102|issue=2|year=2006|pages=240–243|issn=00908258|doi=10.1016/j.ygyno.2005.12.029}}</ref>
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Revision as of 16:33, 23 December 2021

Cervical intraepithelial neoplasia edit
Histology Grade Corresponding Cytology Description Image
CIN 1 (Grade I) Low-grade squamous intraepithelial lesion (LSIL)
  • Mild epithelial dysplasia
  • Confined to the basal 1/3 of the epithelium
 File:LSIL (CIN 1), Cervical Biopsy (3776284166).jpg
CIN 2/3 High-grade squamous intraepithelial lesion (HSIL)[notes 1]
  • Represents a mix of low and high-grade lesions not easily differentiated by histology
CIN 2 (Grade II)[notes 2]
  • Moderate dysplasia confined to the basal 2/3 of the epithelium
CIN 3 (Grade III)[notes 3]
  • Severe dysplasia with undifferentiated neoplastic cells that span more than 2/3 of the epithelium
  • May involve the full thickness
  • May also be referred to as cervical carcinoma in situ
 File:Histopathology of CIN 3.jpg

Notes

  1. ↑ HSIL+ encompasses HSIL, AGC, and cancer
  2. ↑ CIN 2+ encompasses CIN 2, CIN 3, adenocarcinoma in situ (AIS), and cancer
  3. ↑ CIN 3+ encompasses CIN 3, AIS, and cancer


Main page

References

  1. ↑ Nagi, Chandandeep S.; Schlosshauer, Peter W. (2006). "Endocervical glandular involvement is associated with high-grade SIL ". Gynecologic Oncology 102 (2): 240–243. doi:10.1016/j.ygyno.2005.12.029. ISSN 00908258. 

Image sources


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