Seborrheic keratosis: Difference between revisions
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[[File:Histopathology of seborrheic keratosis.jpg|thumb|Seborrheic keratosis]] | [[File:Histopathology of seborrheic keratosis.jpg|thumb|Seborrheic keratosis]] | ||
{{Gross processing of well-defined skin lesions}} | |||
== | ==Microscopic evaluation== | ||
Typical microscopic findings in seborrheic keratosis: | Typical microscopic findings in seborrheic keratosis: | ||
*A localized epidermal proliferation of basaloid and squamoid cells.<ref name="Weidner 2009">{{cite book | last=Weidner | first=Noel | title=Modern surgical pathology | publisher=Saunders/Elsevier | publication-place=Philadelphia, PA | year=2009 | isbn=978-1-4160-3966-2 | oclc=460883320 | page=}}</ref> | *A localized epidermal proliferation of basaloid and squamoid cells.<ref name="Weidner 2009">{{cite book | last=Weidner | first=Noel | title=Modern surgical pathology | publisher=Saunders/Elsevier | publication-place=Philadelphia, PA | year=2009 | isbn=978-1-4160-3966-2 | oclc=460883320 | page=}}</ref> | ||
Revision as of 07:55, 23 October 2019
Author:
Mikael Häggström [note 1]
Gross processing
| <4 mm | 4 - 8 mm | 9 - 15 mm |
|---|---|---|
|
File:Tissue selection from skin excision less than 4 mm with well-defined lesion.png |
File:Tissue selection from skin excision 4-8 mm with well-defined lesion.png |
File:Tissue selection from skin excision 9-15 mm with well-defined lesion.png |
In table above, each top image shows recommended lines for cutting out slices to be submitted for further processing. Bottom image shows which side of the slice that should be put to microtomy. Dashed lines here mean that either side could be used. Further information: Gross processing of skin excisions
Microscopic evaluation
Typical microscopic findings in seborrheic keratosis:
- A localized epidermal proliferation of basaloid and squamoid cells.[2]
- Most commonly a dome-shaped exophytic epidermal growth, containing multiple cornified cysts.[2]
- The proliferating cells are generally round and basaloid.[2]
- Melanin pigment deposition can occur.[2]
- Clinically, the patient is generally elderly.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑
- . Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision. Swedish Society of Pathology.
- For number of slices and coverage of lesions, as well as including sections from each edge in case of diffuse border. - . Dermatopathology Grossing Guidelines. University of California, Los Angeles. Retrieved on 2019-10-23.
- For microtomy of the most central side at the lesion - "The principles of mohs micrographic surgery for cutaneous neoplasia
- With a "standard histologic examination" that, in addition to the lesion, only includes one section from each side along the longest diameter of the specimen.
- It also shows an example of circular coverage, with equal coverage distance in all four directions.
- The entire specimen may be submitted if the risk of malignancy is high. - . Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision. Swedish Society of Pathology.
- ↑ 2.0 2.1 2.2 2.3 Weidner, Noel (2009). Modern surgical pathology . Philadelphia, PA: Saunders/Elsevier. ISBN 978-1-4160-3966-2. OCLC 460883320.
Image sources