Template:Tissue selection from suspected malignant skin lesions: Difference between revisions

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==Gross processing==
==Gross processing==
{|class="wikitable"
{|class="wikitable"
|+ Gross pathologic processing of diffuse skin lesions, by lesion size:<ref name=processing>
|+ Gross pathologic processing of diffuse skin lesions, by lesion size:<ref name=processing>There are many variants for the processing of skin excisions. These examples use aspects from the following sources:
*{{cite web|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision|website=Swedish Society of Pathology}}<br>- For number of slices and coverage of lesions, as well as including sections from each edge in case of diffuse border.
*{{cite web|url=http://www.svfp.se/foreningar/uploads/L15178/kvast/hud/Handlaggning%20av%20hudprover%20%20provtagningsanvisningar%20utskarningsprinciper%20och%20snittning%2020150325.pdf|title=Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision|website=Swedish Society of Pathology}}<br>- For number of slices and coverage of lesions, as well as including sections from each edge in case of diffuse border.
*{{cite web|url=http://pathology.ucla.edu/workfiles/Education/Residency%20Program/Gross%20Manual/SkinExcisionLarge.pdf|title=Dermatopathology Grossing Guidelines|website=University of California, Los Angeles|accessdate=2019-10-23}}<br>- For microtomy of the most central side at the lesion
*{{cite web|url=http://pathology.ucla.edu/workfiles/Education/Residency%20Program/Gross%20Manual/SkinExcisionLarge.pdf|title=Dermatopathology Grossing Guidelines|website=University of California, Los Angeles|accessdate=2019-10-23}}<br>- For microtomy of the most central side at the lesion

Revision as of 10:09, 23 October 2019

Gross processing

Gross pathologic processing of diffuse skin lesions, by lesion size:[1]
<4 mm 4 - 8 mm 9 - 15 mm
File:Tissue selection from skin excision less than 4 mm with diffuse lesion.png File:Tissue selection from skin excision 4-8 mm with diffuse lesion.png File:Tissue selection from skin excision 9-15 mm with diffuse lesion.png

In table above, each top image shows recommended lines for cutting out slices to be submitted for further processing. Bottom image shows which side of the slice that should be put to microtomy. Dashed lines here mean that either side could be used.

Up to the entire specimen may be sliced and submitted if the risk of malignancy is high.[1] Otherwise the rest may be saved in case microscopy indicates further sampling.

  1. 1.0 1.1 There are many variants for the processing of skin excisions. These examples use aspects from the following sources: ". Ochsner J 5 (2): 22–33. 2003. PMID 22826680. PMC: 3399331. Archived from the original. . 
    - With a "standard histologic examination" that, in addition to the lesion, only includes one section from each side along the longest diameter of the specimen.
    - It also shows an example of circular coverage, with equal coverage distance in all four directions.
    - The entire specimen may be submitted if the risk of malignancy is high.