Verrucous oral lesions: Difference between revisions

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==Microscopic evaluation==
==Microscopic evaluation==


Look for signs of koilocyte-like changes, which may indicate verrucous squamous cell carcinoma, and which typically only has low atypia:<ref name="PaolinoDonati2017">Initially copied from: {{cite journal|last1=Paolino|first1=Giovanni|last2=Donati|first2=Michele|last3=Didona|first3=Dario|last4=Mercuri|first4=Santo|last5=Cantisani|first5=Carmen|title=Histology of Non-Melanoma Skin Cancers: An Update|journal=Biomedicines|volume=5|issue=4|year=2017|pages=71|issn=2227-9059|doi=10.3390/biomedicines5040071}} - "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)."</ref>  
Look for signs of koilocyte-like changes, which may indicate verrucous squamous cell carcinoma, and which typically only has low atypia:<ref name="PaolinoDonati2017">{{PaolinoDonati2017}}</ref>  
<gallery mode=packed heights=190>
<gallery mode=packed heights=190>
File:Micrograph of penile verrucous carcinoma - 20x.jpg  
File:Micrograph of penile verrucous carcinoma - 20x.jpg  

Latest revision as of 15:55, 19 June 2022

Author: Mikael Häggström [note 1]

Verrucous hyperplasia.

Verrucous oral lesions have hypergranulosis and/or hyperkeratosis as the most conspicuous finding.

Microscopic evaluation

Look for signs of koilocyte-like changes, which may indicate verrucous squamous cell carcinoma, and which typically only has low atypia:[1]

Verrucous squamous cell carcinoma (images are from penis).

If uncertain, perform immunohistochemistry for Ki67 and p53.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Initially copied from: Paolino, Giovanni; Donati, Michele; Didona, Dario; Mercuri, Santo; Cantisani, Carmen (2017). "Histology of Non-Melanoma Skin Cancers: An Update ". Biomedicines 5 (4): 71. doi:10.3390/biomedicines5040071. ISSN 2227-9059. 
    "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)."

Image sources