Hyperthyroidism
Author:
Mikael Häggström [note 1]
Fixation
Generally 10% neutral buffered formalin. Fix all thyroids at least overnight to avoid artifactual nuclear atypia.[1]
See also: General notes on fixation
Template:Gross processing of thyroid
Microscopic evaluation
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Graves' disease - low magnification: exuberant papillary hyperplasia.
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Graves' disease - medium magnification: cells with round nuclei and even chromatin pattern lining the papillae.
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Amiodarone associated follicular cell damage - high magnification: large thyroid follicles filled with colloid and numerous histiocytes
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Amiodarone associated follicular cell damage - low magnification: large thyroid follicles filled with colloid and numerous histiocytes (arrow heads)
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Papillary hyperplastic nodule - high magnification: oncocytic cells lining the papillary structures (arrow)
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Papillary hyperplastic nodule - low magnification: cystic nodule with papillary architecture (arrow)Papillary hyperplastic nodule - low magnification: cystic nodule with papillary architecture (arrow)
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ . Gross Pathology Manual By The University of Chicago Department of Pathology. Updated 2-14-19 NAC.
Image sources