Granulomatous skin inflammation
Author:
Mikael Häggström [note 1]
- Look for foreign bodies, conferring a diagnosis of foreign body granuloma.
- Look for any specific appearance of the giant cells.
- Look for relation to adnexae or other particular structures.
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Foreign body: Suture granuloma, with multinucleated giant cells surrounding (grey) suture material.
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Relation: Folliculitis with multinucleated giant cells surrounding a hair follicle.
![Appearance: A Touton giant cell contains a ring of nuclei surrounding a central homogeneous cytoplasm, with foamy cytoplasm surrounding the nuclei.[1][2] The central cytoplasm (surrounded by the nuclei) may be both amphophilic and eosinophilic.[3]](/index.php?title=Special:Upload&wpDestFile=Touton_giant_cell_(annotated).jpg){kind=link}
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
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References
- ↑ Grant-Kels, Jane (2007). Color Atlas of Dermatopathology . City: Informa Healthcare. pp. 107, 119. ISBN 978-0-8493-3794-9.
- ↑ Carmen Gómez-Mateo, Maria; Monteagudo, Carlos (2013). "Nonepithelial skin tumors with multinucleated giant cells ". Seminars in Diagnostic Pathology 30 (1): 58–72. doi:. PMID 23327730. Archived from the original. .
- ↑ Sequeira, Fiona; Gandhi, Suneil (2012). "Named cells in dermatology ". Indian Journal of Dermatology, Venereology and Leprology 78 (2): 207–16. doi:. PMID 22421663. Archived from the original. .
Image sources